Supervised Group Based Exercise for Men With Prostate Cancer on Androgen Deprivation Therapy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Prostatic Neoplasms
- Sponsor
- Herlev Hospital
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- Change in 30second Chair-Stand test (30s-CST)
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
Exercise intervention for men with prostate cancer on androgen deprivation therapy.
Detailed Description
The aim of the project is to investigate the effects of patient education and exercise intervention implemented in daily clinical practice for men with prostate cancer on androgen deprivation therapy * Functional capacity * Quality of life * Body composition * Blood pressure and to assess safety of progressive resistance training for participants with bone metastases.
Investigators
Peter Busch Østergren
M.D.
Herlev Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients with a prostate cancer diagnosis on androgen deprivation therapy
Exclusion Criteria
- •Opioid demanding treatment for skeletal pain
- •Eastern Cooperative Oncology Group performance status \> 2
- •Inability to perform floor and machine exercises independently
Outcomes
Primary Outcomes
Change in 30second Chair-Stand test (30s-CST)
Time Frame: Baseline, 12 and 24 weeks
Test of functional capacity, measured as change
Change in Graded Cycling Test with Talk Test (GCT-TT)
Time Frame: Baseline, 12 and 24 weeks
Test of functional capacity, measured as change
Secondary Outcomes
- change in QoL(Baseline, 12 and 24 weeks)
- change in Body composition(Baseline, 12 and 24 weeks)
- change in Bloodpressure(Baseline, 12 and 24 weeks)
- Safety of exercise assessed by serious adverse events according to the FDA(Study period baseline - 24 weeks)
- Compliance assessed by attendance and continued exercise (yes/no)(Baseline, 12 and 24 weeks)