跳至主要内容
临床试验/CTRI/2021/06/034469
CTRI/2021/06/034469尚未招募不适用

Cardiovascular Manifestation In Moderate ToSevere COVID-19 Patients Undergoing Treatment InCritical Care Unit Of A Tertiary Care Hospital,West Bengal And Role Of Portable, Point Of CareCardiac Biomarker Autoanalyzer In Their EarlyDiagnosis.

MEDICAL COLLEGE KOLKATA1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2021年1月7日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
150
试验地点
1
主要终点
Discharge from CCU

研究概览

简要总结

Hospitalised patients admitted with fever, cough, sore throat and/ dyspnoea who will be tested positive for SARS COV-2 and have moderate to severe disease activity will be included in our study. The electronic medical charts of the study subjects will be reviewed and relevent demographic, clinical, laboratory and imaging findings will be de-identified and recorded. Demographic characteristics including age at the time of diagnosis, gender, race, BMI will be collected. Past medical history including coronary artery disease, heart failure with reduced or preserved left ventricular Ejection Fraction, AF, Hypertension, Dyslipidemia, DM, Smoking history as well as history of regular medication will be ascertained.  Laboratory investigation for Cardiac biomarkers like Troponin I, BNP, Pro BNP, CPK, CPKMB and other investigations like D dimer, Serum electrolytes, Hemoglobin, Creatinine, Lactate will be collected. Available EKG, TTE will be individually reviewed by an independent cardiology faculty or fellow. The incidence and relative frequencies of different cardiovascular disease manifestations occurring denovo among the moderate to severely affected Covid patients at Intensive care facility will be noted. Finally clinical outcomes including need for mechanical ventilation, length of ICU/CCU stay, length of hospilalisation, arrythmias, cadiac arrest and in hospital mortality will be abstracted.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • Laboratory confirmed COVID-19 patients SpO2 <94% Patients on different modalities of oxygen therapy Patients with radiologically confirmed pneumonia Suffering from ARDS / Acute Respiratory Failure.

排除标准

  • Patients unwilling to participate in the study.

结局指标

主要结局

Discharge from CCU

时间窗: 28 days

All cause mortality

时间窗: 28 days

次要结局

  • Association between existing cardiac disease or new onset cardiac manifestations among Covid infected patients.(28 days)

研究者

申办方类型
Government medical college

研究点 (1)

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