Exploratory study of hyaluronic acid vocal cord injection in the treatment of vocal cord insufficiency
Not Applicable
Recruiting
- Conditions
- vocal cord insufficiency
- Registration Number
- ChiCTR2400088933
- Lead Sponsor
- Beijing Luhe Hospital,Capital Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Age 18-85 years old, male or female.<br>2) Unilateral vocal cord paralysis or injury, poor glottal closure.<br>3) The course of the disease is greater than one month.<br>4) At least two GRBAS scores of 2 or above.<br>5)Subjects read and fully understand the study instructions and sign the informed consent form
Exclusion Criteria
- Those who are engaged in over-pronunciation occupations and cannot get out of it.<br>2) Patients with abnormal function of vital organs, such as heart, lungs, liver, and kidneys.<br>3) Pregnant or lactating women, or those who plan to give birth in the near future.<br>4) Those who have a history of allergies to a variety of drugs.<br>5) Those who are unable to follow up or cooperate for a long time.<br>6) Those who have participated in other clinical trials within the last 3 months.<br>7) Those with progressive severe disease.<br>8)Alcoholics or drug addicts.<br>9) Those who cannot follow the clinical trial protocol due to severe mental disorder or language disorder.<br>10) There are factors that damage the voice in life and cannot be avoided.<br>11)There are any conditions in the study that are considered inappropriate for enrollment.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method voice handicap index;
- Secondary Outcome Measures
Name Time Method Subjective auditory perception assessment;Objective acoustic assessment;vocal cord physical state assessment; imaging assessment;