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Clinical Trials/CTRI/2022/09/045880
CTRI/2022/09/045880
Recruiting
未知

ââ?¬Å?A prospective case control study to evaluate the cardiovascular functions by global longitudinal strain (GLS) echocardiography and brachial artery flow mediated dilatation in patients with ANCA associated vasculitisââ?¬?

PGIMER Chandigarh0 sites0 target enrollmentTBD

Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
PGIMER Chandigarh
Status
Recruiting
Last Updated
3 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
3 years ago
Study Type
Observational

Investigators

Eligibility Criteria

Inclusion Criteria

  • 1\. Patients between 18 and 70 years of age, previously diagnosed cases of ANCA associated vasculitis, who have been in remission for more than 06 months, will be included in the study group. 2\. Age and sex\-matched healthy controls will be included the control group 3\. Patient understands and agrees to comply with all specified study requirements and provides written Informed Consent to this effect.

Exclusion Criteria

  • 1\. Patients with clinical instability with compromised hemodynamics including (not restricted to)
  • a. Symptomatic decompensated heart failure
  • b. Renal failure requiring renal replacement therapy
  • c. Shock due to any cause
  • 2\. Patients with a medical condition that limits the life expectancy to less than one year
  • 3\. Women who are pregnant or planning to be pregnant
  • 4\. Patients with history of Diabetes mellitus
  • 5\. Patients with history of smoking
  • 6\. Patients with history of premature CAD in a first degree relative (in men aged 45 years, in women aged 55 years)
  • 7\. Patients with history of sildenafil use

Outcomes

Primary Outcomes

Not specified

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