Improvement of endogenous regeneration in normal healthy volunteers through physical exercise REBIRTH aktiv”

Not Applicable

• Conditions: Physical inactivity

• Registration Number: DRKS00003097
• Lead Sponsor: MHH - HTTG-Chirurgie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2011-05-26
• Study Completion: 2012-05-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: Male
• Target Recruitment: 76

Inclusion Criteria

Male subjects in a preferentially sitting working place situation conducting no physical training.

Exclusion Criteria

Smoking, Diabetes mellitus, Surgical interventions 6-8 weeks prior to the start of the study, artificial joints implanted less than 6 months prior to the start of the study, coronary heart diseases or arterial obstructive disesases, non-adjusted hypertension, cancer and other diseases that constrain physical training.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Activity of telomerase measured by TRAP-Assay at baseline and month 1, 2, 3, and 6.

Secondary Outcome Measures

Name	Time	Method
The achievement potential (ergospirometry), working index (questionnaire), Periodontal health (Probing using a Florida probe) and endothelial function (Endo-PAD, Vicorder) will be measured at baseline and after 1, 2, 3 and 6 months.