Prone Positioning for Brain-injured Patients With Severe ARDS (ProBrain)

Completed

• Conditions: Cerebral Blood Flow

• Registration Number: NCT05050838
• Lead Sponsor: Fondation Ophtalmologique Adolphe de Rothschild

Brief Summary

Prone position (PP) is a key component to treat hypoxemia in patients with severe acute respiratory distress syndrome (ARDS). However, most studies evaluating PP effects in patients with ARDS exclude those with brain-injuries without providing any medical evidence. This prospectice observational study aimed to investigate if prone positioning leads to significant modification of cerebral perfusion in brain-injured patients with ARDS.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-08-01
• Primary Completion: 2020-06-30
• Study Completion: 2020-06-30
• Status Verified: 2021-09
• Study First Submitted: 2021-09-09
• Study First Submitted QC: 2021-09-10
• Last Update Submitted: 2021-09-10
• Study First Posted: 2021-09-21
• Last Update Posted: 2021-09-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Not specified
• Target Recruitment: 11

Inclusion Criteria

• adult's patients suffering from brain injuries
• patients neurologically monitored with TCD
• patients requiring prone position for severe ARDS

Exclusion Criteria

• pregnant women
• patients with contrindication to prone position

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cerebral Blood Flow	1 hour	Cerebral Blood Flow measurement before and after prone positioning

Trial Locations

Locations (1)

Hôpital Fondation Adolphe de Rothschild; 🇫🇷 Paris, Ile-de-France, France