Respiratory Muscle Stretching in Chronic Obstructive Pulmonary Disease (COPD)

Phase 4

Completed

• Conditions: Chronic Obstructive Pulmonary Disease
• Interventions: Behavioral: respiratory muscle stretching

• Registration Number: NCT00935181
• Lead Sponsor: Faculdade Evangelica do Parana

Brief Summary

Objective: The investigators studied the effects of respiratory muscle stretching in an 8-week pulmonary rehabilitation program. Methods: This was a simple-blind parallel controlled trial, conducted an out-patient clinic. Twenty six patients with COPD (mean age 68 ± 6 y, percent of predicted FEV1 47 ± 16) were randomized to either respiratory muscle stretching group plus exercise training (RMS), and exercise training group (Sham), in an 8-week exercise program that had 3 sessions per week. The investigators measured inspiratory and expiratory muscle strength (by maximal inspiratory and expiratory pressure - PIM and PEM), exercise capacity (by 6-minute walk distance), dyspnea and quality of life.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-01
• Primary Completion: 2006-12
• Study Completion: 2008-12
• Study First Submitted: 2009-06-29
• Status Verified: 2009-07
• Study First Submitted QC: 2009-07-07
• Last Update Submitted: 2009-07-07
• Study First Posted: 2009-07-08
• Last Update Posted: 2009-07-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 26

Inclusion Criteria

• Subjects between 40 and 75 years of age referred by a physician to the Pulmonary Rehabilitation Program
• With a clinical and spirometric diagnosis of moderate to severe COPD according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD), in a stable condition (without exacerbations or infections for at least a month)
• Former smokers

Exclusion Criteria

• Patients with a known history of asthma, or severe and/or unstable heart disease
• Any other pathological condition that could impair their physical activities

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
exercise training program	respiratory muscle stretching	The exercise training program consisted of three 90-minute sessions per week for eight weeks. Each session consisted of a stretching exercise, resistance that patients started at 70% of the initial one-repetition maximum (1RM: the maximum load which can be moved only once over the full range of motion without compensatory movements) in the first week (3x8 repetitions). Every week the load was increased by 5% of the 1RM, and endurance training (treadmill walking speed was set at 60% of the average speed obtained from the 6MWT (6MWTpeak) for 10 mins in the first week and was increased to 20 mins in week 8

Primary Outcome Measures

Name	Time	Method
Inspiratory muscle strength	2 hours

Secondary Outcome Measures

Name	Time	Method
Exercise capacity	2 hours

Trial Locations

Locations (1)

Faculdade Evangelica do Paraná; 🇧🇷 Curitiba, Paraná, Brazil