NCT04071964进行中（未招募）不适用
Gut Microbiota, Anastomotic Leak and Colorectal Cancer
Centre hospitalier de l'Université de Montréal (CHUM)1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2019年7月9日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Number of participants with an anastomotic leak
研究概览
简要总结
This is a prospective study evaluating the relation between the gut microbiota composition, intestinal healing after colorectal surgery and colorectal cancer behavior.
Our hypothesis is that the gut microbiota composition could predict poor intestinal healing in colorectal surgery, and that the gut microbiota might have an impact on colorectal cancer clinical behavior and may predict disease outcomes.
详细描述
No more details required
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18 years and older
- •CRC diagnosis
- •Upcoming colonic and/or rectal resection with/without anastomosis
- •Individuals without diseases of the colon and rectum (healthy controls)
排除标准
- •Pregnancy
- •Previous stoma
- •Bowel surgery in the last 4 weeks prior to the surgery
- •Secondary objectives, inclusion criteria are as follows:
- •Age 18 years and older
- •Rectal cancer diagnosis with histopathological confirmation
- •Abdominoperineal resection with terminal colostomy
- •Expectative non-surgical management ("Watch and wait approach")
结局指标
主要结局
Number of participants with an anastomotic leak
时间窗: 1 month
Clinical and/or radiological anastomotic leak
次要结局
- Number of participants with cancer reoccurence(3 years)
研究者
研究点 (1)
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