Evaluating the effect of conventional local anaesthesia anaesthesia (lignocaine), warming it and adding a buffer on the success of a nerve block in lower primary posterior teeth

Phase 2

Completed

• Conditions: children aged 6-12 years, with bilateral vital pulp involvement in primary mandibular molars.

• Registration Number: CTRI/2017/02/007922
• Lead Sponsor: Reenu Sarah Kurien

Brief Summary

This study is a randomized, double blinded, split mouth clinical trial, comparing the anaesthetic efficacy and patient’s pain reaction to warm lignocaine, buffered lignocaine and conventional 2% lignocaine during pulp therapy in primary mandibular molars. 50 patients were randomly divided into 2 groups and were given conventional lignocaine on one visit on one side and either buffered or warmed lignocaine on the other side during the next visit. The results showed that the pain on administration, mean onset of anaesthesia, pain during pulp therapy, the parameters of the SEM score and the duration of anaesthesia were all significantly lower for the buffered and warmed solutions compared to the conventional solution. However there was no significant difference on comparing the warmed and buffered groups with each other. Thus it can be concluded that modifying local anaesthesia by either buffering it or warming it can be beneficial in reducing the pain on injection and during pulp therapy, especially in children.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-11-30
• Last Update Posted: 2018-09-20

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• 1.patients having deep dentinal caries extending through half the dentinal depth wrt 74, 75, 84, 85 2.
• patients complaining of mild to moderate pain.
• 3.teeth with vital pulp 4.children with frankl behaviour rating of 3 or 4 5.patients whose parents/guardians give consent 6.subjects should be free of systemic disease 7.the agreement to comply with study visits and procedures.

Exclusion Criteria

• 1.patients who are physically or medically compromised/ systemic disease 2.patients with allergies to local anaesthetics, sulphites or sodium bicarbonate 3.patients on any medication 4.presence of abscess or sinus openings at the site of injection or at the tooth involved.
• 5.children with frankl behaviour rating of 1 or 2.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.Anaesthetic efficacy	3-5 hours
2.The patient’s pain reaction	3-5 hours

Secondary Outcome Measures

Name	Time	Method
1.Pain during administration of anaesthesia	2.Onset of anaesthesia

Trial Locations

Locations (1)

I.T.S Dental College, Hospital And Research Centre; 🇮🇳 Nagar, UTTAR PRADESH, India

I.T.S Dental College, Hospital And Research Centre

🇮🇳Nagar, UTTAR PRADESH, India

Reenu Sarah Kurien

Principal investigator

9873825939

kurienreenu7@gmail.com