Performance of Non-injected MR Enterography Compared to a Conventional MR Enterography Protocol With Contrast Agent Injection
- Conditions
- Crohn Disease
- Interventions
- Device: MRI
- Registration Number
- NCT06526234
- Lead Sponsor
- Central Hospital, Nancy, France
- Brief Summary
Entero-MRI is indicated in Crohn's disease as part of the initial work-up or follow-up (to assess response to treatment, complications). The protocol for carrying out the examination complies with precise specifications set out in international recommendations. To perform the test, the small intestine must be distended with a hyperosmolar product. This protocol is applied to all patients, with no distinction or adaptation.
The total duration of the examination is sometimes difficult for patients to bear. Ingestion of the product to obtain distension of the small intestine is often poorly tolerated by patients.
In a number of cases, the entero-MRI may have been normal due to symptomatology regression or other diagnosis. The patient therefore underwent a complete examination similar to that of a patient with a pathology requiring characterization.
In this context, the investigators hypothesize that fast MR sequences are sufficient to discriminate between normal and abnormal examinations.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 500
Patient with MR enterography examination for follow-up or suspected Crohn's disease
No Exclusion Criteria.
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Patients with Crohn's disease or suspected Crohn's disease MRI -
- Primary Outcome Measures
Name Time Method Presence or absence of lesions detected visually by a radiologist on injection-free sequences versus conventional MR enterography. Baseline (day 0)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
CHRU Nancy
🇫🇷Vandœuvre-lès-Nancy, CHRU De Nancy, France