Association between carperitide infusion and shedding of the endothelial glycocalyx in cardiac surgical patients

Not Applicable

• Conditions: Postoperative cardiac surgery patients recieving carperitide infusion therapy

• Registration Number: JPRN-UMIN000036677
• Lead Sponsor: Hokkaido University Hospital Anesthesiology, IC

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-05-08
• Study Completion: 2022-06-30
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

Not provided

Exclusion Criteria

1.A patient who have had recieved carperitide infusion within 12h 2.A patient with wobbly tooth 3.A patient who have surgical history of tongue 4.A patient without any indwelling arterial line 5.A patient determined to be inappropriate as a research subject by the principal investigator

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in Perfused Boundary Region (PBR) [Time frame: just before the start of carperitide infusion, 1h, 2h, 6h after the start of infusion]

Secondary Outcome Measures

Name	Time	Method
Change in plasma syndecan-1 concentration, RBC column width, RBC filling [Time frame: just before the start of carperitide infusion, 1h, 2h, 6h after the start of infusion]