Electromyography to assess the change in muscle activity as a result of intrathecal baclofen treatment
- Conditions
- spasticity10029317
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 32
Inclusion Criteria
• Receiving an intrathecal baclofen trial (single shot baclofen test or
external intrathecal baclofen pump implantation) or permanent intrathecal
baclofen pump implantation
• Unilateral or bilateral spasticity of lower limbs
• Modified Ashworth Scale and electromyography measurements possible (18,5 *
BMI < 30)
• Able to understand and comply to verbal instructions
Exclusion Criteria
• Age under 18 years old
• High sensitivity of lower limb skin
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study endpoint is the change in muscle activity measured by EMG. The<br /><br>change in muscle activity is assessed by analysis of the amplitude, the root<br /><br>mean square, the power spectral density and the co-contraction index of the EMG<br /><br>signals. The EMG signals are measured during rest, during the MAS assessment<br /><br>and during voluntary contraction by the participant. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary study parameters are the MAS indices of the participants before and<br /><br>after ITB treatment and the Patient Global Impression of Change reported by the<br /><br>participants, and the correlation between de EMG features and MAS and PGIC.</p><br>