Comparison of an Acceleromyography- and Electromyography-based Neuromuscular Monitor With TOF-Watch ® Monitor
- Conditions
- Neuromuscular Blockade
- Registration Number
- NCT05632107
- Lead Sponsor
- Huazhong University of Science and Technology
- Brief Summary
A quantitative neuromuscular monitoring device is desirable to titrate the depth of neuromuscular block (NMB) during a procedure, and to prevent residual effects after removal of the endotracheal tube. Unfortunately, the most widely used monitoring technique acceleromyography (AMG) typically implies a series of cumbersome installation and calibration procedures that frequently precludes correct use of these devices in clinical practice. Electromyography (EMG) has recently attracted a lot of attention as an alternative strategy to compensate for the deficiency of AMG-based neuromuscular monitors. Nowadays, a new technology that allows for the simultaneous acquisition of EMG and AMG signals is commercially available. Although its reliability has been rapidly accepted in Physical Medicine and Rehabilitation, the use of the technique in neuromuscular monitoring has never been reported. The aim of the present study is to assess the validity of the new device for estimating the neuromuscular block by comparing with TOF Watch®-SX, which is the most widely accepted AMG-based neuromuscular monitor that has been practiced in the clinical arena for decades.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 100
- Age less than 18 yr
- American Society of Anesthesiologists Physical Status I to III
- Elective surgery requiring muscle relaxation
- Patients participated voluntarily and signed informed consent
- Patients with known neuromuscular disorder
- Stroke
- Patients with a history of allergic reaction toneuromuscular blocking agents
- Use of medications that might interfere with neuromuscular transmission
- Any previous injury to the examined arm that might influence nerve conduction parameters
- Pacemaker
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Assessing the correlation between the posttetanic count (PTC) obtained from the 2 devices Perioperative data Assessing the correlation between the train-of-four (TOF) obtained from the 2 devices Perioperative data
- Secondary Outcome Measures
Name Time Method Screening for eligible individual signal sources from the multiplex information of the new technology for improving neuromuscular monitoring Perioperative data
Trial Locations
- Locations (2)
Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
🇨🇳Wuhan, Hubei, China
Department of Anaesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology
🇨🇳Wuhan, Hubei, China