NCT00097955已完成2 期
Safety and Efficacy of Aliskiren When Added to Standardized Losartan and Optimal Antihypertensive Therapy in Patients With Hypertension, Type 2 Diabetes and Proteinuria
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 496
- 试验地点
- 12
- 主要终点
- Change from baseline in urinary albumin creatinine ratio after 24 weeks
研究概览
简要总结
Study of the efficacy and safety of aliskiren when added to losartan and optimal antihypertensive therapy in patients with hypertension, type 2 diabetes, and kidney disorders to monitor improvement in any of these conditions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hypertension
- •Elevated urinary protein levels
- •Confirmed type 2 diabetes
排除标准
- •Certain diseases
- •Uncontrolled diabetes
- •Type 1 diabetes
结局指标
主要结局
Change from baseline in urinary albumin creatinine ratio after 24 weeks
次要结局
- Equal/more than 50% reduction from baseline in urinary albumin creatinine ratio after 24 weeks
- Change from baseline in urinary albumin excretion rate after 24 weeks
研究者
研究点 (12)
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