on-invasive Measurements of Intestinal Failure-Associated Steatosis among adult patients.
Completed
- Conditions
- leverproblematiek bij darmfalen (IFALD)fatty liverIntestinal failure-associated liver disease (IFALD)10019654
- Registration Number
- NL-OMON45917
- Lead Sponsor
- Radboud Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
* Use of parenteral nutrition and/ or intravenous fluids > 3 months, at least 2 times per week ten gevolge van darmfalen
Exclusion Criteria
* BMI > 30 kg/m2
* Metastasized malignancy, or malignancy currently under treatment
* Pregnancy or breastfeeding
* Severe claustrophobia, presence of metallic implants, or not able to undergo MR measurements of the liver due to other reasons
* Blood transfusion or transfusion with a ferric compound within one month of study
* Subject have had a liver transplantation in the past
* Subject has a history of non-medical substance drug abuse within the 6 months prior to study start
* Known obstructive cholestasis at time of measurements (yes/no)
* Major / systemic infection at time of measurement
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Steatosis severity (%)</p><br>
- Secondary Outcome Measures
Name Time Method <p>Presence or absence of steatosis (<5.6%/*5.6%).</p><br>