MedPath

Study of the effects of adding remifentanil to anesthetic drugs before succinylcholine on post operative myalgia

Phase 2
Conditions
Condition 1: post operative pain. Condition 2: Skeletal muscle relaxants.
Myalgia
Skeletal muscle relaxants [neuromuscular blocking agents]
Registration Number
IRCT138712241766N1
Lead Sponsor
Kurdistan university of medical siences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
60
Inclusion Criteria

American Society of Anesthesiologists (ASA) physical status I or II, ambulatory urological or gynecological surgery under general anesthesia. Exclusion criteria : arrhythmia, hypo- or hypertension, hyperkalemia, increased intraocular pressure, increased intracranial pressure, presenting a difficult airway, pregnant, treatment with any drug known to interact with neuromuscular function, and significant renal, neuromuscular, or hepatic disease.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Muscle fasciculation. Timepoint: after adminstration of succinylcoline. Method of measurement: Observational by 4-point scale: no fasciculation= 0; mild, fine fasciculation of the eyes, neck, face or fingers without limb movement = 1; moderate fasciculation occurring at more than two sites or obvious limb movement = 2; vigorous or severe, sustained, and widespread fasciculation = 3.;Post operative pain. Timepoint: 1 ,6 and 24 hours after operation. Method of measurement: 4-point scale: nil = no muscle pains or stiffness; mild = muscle pains or stiffness at one site but not causing disability or limiting activities; moderate = muscle pains or stiffness at more than one site but not causing disability or limiting activities; severe = muscle pains or stiffness at one site or more and causing disability or limiting activities, e.g., difficulty getting out of bed or turning the head.
Secondary Outcome Measures
NameTimeMethod
Blood pressure changes. Timepoint: before induction of anesthesia and after ending fasciculation. Method of measurement: automated oscilometer.;Heart rate changes. Timepoint: Before induction of anesthesia and after ending fasciculation. Method of measurement: BSI (passport2) automated monitor.
© Copyright 2025. All Rights Reserved by MedPath