Trends in Intellectual Development in Down Syndrome

• Conditions: Down Syndrome

• Registration Number: NCT00954382
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

Previous foreign studies revealed that the IQ in Down syndrome (DS) declines with age, but not any investigation of domestic data in Taiwan was available. Individuals with DS are characterized by limited verbal development, and in this article, authors look into the diverging verbal-nonverbal abilities in the DS phenotype.

Detailed Description

The present study investigated this by analysis the test results of development /intelligence scales. To compare initial cross-sectional data with longitudinal follow-up, about 12 people with DS were included.

Study Timeline

• Study Start: 2009-05
• Study First Submitted: 2009-08-05
• Study First Submitted QC: 2009-08-06
• Study First Posted: 2009-08-07
• Primary Completion: 2009-12
• Status Verified: 2010-03
• Last Update Submitted: 2010-03-16
• Last Update Posted: 2010-03-18
• Study Completion: 2010-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Down syndrome with psychological test results

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Exclusion Criteria

• Comorbidity of severe Autism or visual/auditory impairment

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
IQ	2001-2010

Secondary Outcome Measures

Name	Time	Method
mental age	2001-2010

Trial Locations

Locations (1)

NTUH; 🇨🇳 Taipei, Taiwan