SLCTR/2017/039
Not Yet Recruiting
N/A
A Randomized Controlled Trial to compare the efficacy of topical Ayurvedic oil preparation against placebo in symptomatic knee osteoarthritis
niversity Grants Commission, Sri Lanka0 sitesTBD
ConditionsKnee Osteoarthritis
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Knee Osteoarthritis
- Sponsor
- niversity Grants Commission, Sri Lanka
- Status
- Not Yet Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Diagnosis of symptomatic knee osteoarthritis (KOA) according to the American College of Rheumatology (ACR) radiological and clinical criteria, with a functional scale between i – iii.
- •2\. Radiographic evidence of knee osteoarthritis (osteophytes, joint space narrowing)
- •3\. Knee pain (3\-4 pain flares per month) along with three out of the following six
- •a. Age \>50 years and \<70 years
- •b. Joint stiffness lasting for less than 30 minutes
- •c. Joint crepitus
- •d. Bony tenderness
- •e. Bony enlargement
- •f. No palpable warmth
- •4\. Ability to identify a predominantly painful (index) knee with moderate pain in the index knee, defined by pain on walking on a flat surface, pain at rest and climbing upstairs rated as 4 or 5 for questions of the the Western Ontario and McMaster Universities Arthritis Index \[WOMAC \- 11 point numerical rating scale (NRS), v. 3\.1] and a total average WOMAC pain sub scale score of \<7 at the first (B1\) and second (B2\) baseline visits five days apart.
Exclusion Criteria
- •1\. Inflammatory diseases
- •2\. History of total knee replacement
- •3\. Long term use of non\-steroidal anti\-inflammatory drugs (Patients will be required to withdraw from topical non\-steroidal anti\-inflammatory drugs for 48 hours prior to recruitment)
- •4\. Serious co\-morbidities (e.g. any form of debility that restricts independent movement, stroke, chronic renal failure and inadequate mental capacity to participate in the study)
- •5\. Difference in pain rating (determined from questions of WOMAC) or the difference in the total average pain score between the B1 and B2 over 2\.
- •6\. Skin lesions or dermatological diseases in the treatment area
- •7\. Symptomatic ipsilateral hip osteoarthritis or predominant patello\-femoral knee osteoarthritis
- •8\. Non\-index knee pain, or any other pain condition requiring the chronic use of pain medication
- •9\. Intra\-articular injections of hyaluronic acid within 3 months before or during the study
- •10\. Use of oral, inhaled, parenteral corticosteroids within 2 months before or during the study
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Phase 4
To determine which is better in Nephrotic syndrome: Levamisole given once daily or once every alternate day.CTRI/2015/10/006257Dr Sushmita Banerjee196
Completed
N/A
Treatment of convergence insufficiencyCTRI/2018/05/013560ALL INDIA INSTITUTE OF MEDICAL SCIENCES RISHIKESH80
Not Yet Recruiting
N/A
A study on infraclavicular block ultrasound for upper limb surgeriesCTRI/2022/06/043301SRM Medical College Hospital
Active, Not Recruiting
Phase 1
A Randomised controlled trial to compare the efficacy of two types of local anaesthetic blocks in carpal tunnel decompression surgeryCarpal Tunnel SyndromeEUCTR2005-003513-32-GBSouth Tees Hospitals NHS Trust20
Recruiting
N/A
A clinical interventional study to compare the efficacy of two combined non invasive brain stimulation as motor enhancement therapy for upper extremity in brain attack due to blocked blood vessel cases of more than six months.Health Condition 1: I633- Cerebral infarction due to thrombosis of cerebral arteriesCTRI/2019/11/022009JIPMER