Establishment of a Non-invasive and Indirect Measure of Volitional Pimax

Completed

• Conditions: Respiratory Failure; Neuromuscular Diseases

• Registration Number: NCT02242162
• Lead Sponsor: Centre d'Investigation Clinique et Technologique 805

Brief Summary

Respiratory failure is the main death cause in muscular diseases. Non-invasive and volitional measures of inspiratory muscles strength include the nasal pressure with an occluded nostril and the maximal inspiratory pressure (PImax).Unfortunately, volitional maneuvers depend of patient effort. The mean of this reseach is to validate a non-invasive and non-volitional technique to evaluate diaphragm strength at muscular diseases patients.The methdology consist to compar PImax measure to nerves magnetical stimulation maneuvers measure.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-05
• Study First Submitted: 2014-09-15
• Study First Submitted QC: 2014-09-15
• Study First Posted: 2014-09-16
• Primary Completion: 2016-01
• Study Completion: 2016-01
• Status Verified: 2016-03
• Last Update Submitted: 2016-03-01
• Last Update Posted: 2016-03-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

• Neuromuscular disease
• Pimax evaluation indication

Exclusion Criteria

• pregnant women
• usual contre-indications for nuclear magnetic resonance

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
magnetic stimulation pressure measure( Pstim)	10 minutes	phrenic nerves magnetic stimulations

Trial Locations

Locations (1)

Hopital R Poincaré; 🇫🇷 Garches, France