Volontary Inspiratory Muscles Measures Compared With Phrenic Nerves Magnetic Stimulations Measures
Not Applicable
Terminated
- Conditions
- Respiratory FailureNeuromuscular Diseases
- Registration Number
- NCT02078050
- Lead Sponsor
- Centre d'Investigation Clinique et Technologique 805
- Brief Summary
Respiratory failure is the main death cause in neuromuscular diseases. Non-invasive and volitional measures of inspiratory muscles strength include the nasal pressure with an occluded nostril (Psnip) and the maximal inspiratory pressure (PImax). Unfortunately, volitional maneuvers depend of patient effort. The aim of this research is to validate a non-invasive and non-volitional technique to evaluate diaphragm strength at neuromuscular diseases patients. The methodology consists to add to PImax and Psnip measures 5 phrenic nerves magnetical stimulation maneuvers (Pstim).Stimulations will be realize at 3 inspiratory pression levels (0, -1 cm H2O and -5 cm H2O).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 54
Inclusion Criteria
- 18 years old and more men or women
- neuromuscular diseases
- Pimax and Snip evaluation Indication
Exclusion Criteria
- pregnant women
- Usual contre-indications for nuclear magnetic resonance
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Magnetic stimulation pressure measure (Pstim), according to 3 conditions : Pstime, Pstim-5 and Pstim-1 (measured in cmH20). The condition which is most correlated with maximal inspiratory pressure (Pimax or Psnip) is selected. 10 minutes
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Hopital R. Poincaré
🇫🇷Garches, France
Hopital R. Poincaré🇫🇷Garches, France