Comparison of magnesium sulphate versus dexmeditomidine as an adjuvant to ropivacaine for caudal block in paediatric surgeries : a prospective randomized double blind study.
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/08/035876
- Lead Sponsor
- Dr YENDETI AMRUTHA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
i. Children with informed written consent from their parents.
ii. Children posted for infra umbilical surgeries.
iii. American Society Anesthesiologists (ASA) physical status Grade I and II.
iv. Age between 2 to 10 years of either sex.
Exclusion Criteria
i. Anatomical malformation of spine
ii. History of neurological and neuromuscular disorders.
iii. Coagulation abnormalities
iv. Patients with infection at local site.
v. Patients with known allergy to local anesthetics.
vi. Patient with bloody tap and dural puncture during caudal block
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Duration of analgesiaTimepoint: Post-operative analgesia will be monitored through The Face, Legs, Activity, Cry, Consolability (FLACC) pain score immediately with recovery, and every 30 min until the 2nd hour, then at the 4th, 6th, 12th,18th, and 24th hours
- Secondary Outcome Measures
Name Time Method 1. Hemodynamic parameters(Heart rate (HR), Systolic BP(SBP), Diastolic BP(DBP) , Mean Arterial Pressure (MAP), SpO2, Respiratory rate(RR) ) <br/ ><br>2. Onset of analgesia <br/ ><br>3. Residual motor block <br/ ><br>4. Sedation score <br/ ><br>5.To study the adverse effects such as nausea, vomiting, bradycardia ,hypotension, respiratory depression <br/ ><br>Timepoint: <br/ ><br>Hemodynamic parameters will be monitored at 0, 15 and 30 min following caudal block, and at the end of surgery and Postoperatively every 30 min for first two hours, at 4,6,12,18 and 24th hour. <br/ ><br>Post-operative analgesia, sedation and Residual motor blockade will be monitored immediately with recovery, and the 1st, 2nd, 3rd, 4th, 6th, 8th, 12th, 18th, and 24th hours postoperatively. <br/ ><br>Adverse effects monitored and managed for 24 hrs. <br/ ><br>