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Influence of Caffeinated and Non-caffeinated Pre-workout Supplements on Resistance Exercise Performance

Not Applicable
Completed
Conditions
Resistance Training
Caffeine
Dietary Supplements
Interventions
Dietary Supplement: Caffeinated pre-workout supplement
Dietary Supplement: Non-caffeinated pre-workout supplement
Dietary Supplement: Placebo
Registration Number
NCT04712578
Lead Sponsor
Texas Tech University
Brief Summary

This study is a randomized, double-blind, placebo-controlled crossover trial examining the effects of caffeinated and non-caffeinated pre-workout supplements on resistance exercise performance. Resistance-trained adults will be randomly assigned to complete three study conditions (caffeinated pre-workout, non-caffeinated pre-workout, and placebo) in one of the six possible condition orders. During each condition, participants will report to the laboratory for ingestion of the assigned beverage and subsequent muscular performance testing. Major performance outcomes will be force production variables from a mechanized squat device and maximal strength and muscular endurance on the bench press and leg press exercises.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
24
Inclusion Criteria
  • Between the ages of 18 and 40;
  • Body mass between 50 - 100 kg (110-220 lb)
  • Generally healthy (defined as an absence of any disease or medical condition which could potentially be negatively affected by consumption of the commercially available dietary supplements or performance of exercise, including but not limited to musculoskeletal or cardiovascular diseases).
  • Resistance-trained, defined as completing 2+ resistance training sessions per week for at least three months prior to screening.
  • Participants must have reported regular training of the lower body through a multi-joint exercise such as the squat or leg press at least once weekly during the three-month period prior to screening.
  • Participants must have reported regular training of the bench press or chest press variation at least once weekly during the three-month period prior to screening.
  • Female participants will be required to bench press ≥ 0.5 x body mass and leg press ≥ 1.75 x body mass during initial 1RM assessments to be eligible for this study.
  • Male participants will be required to bench press ≥ 1.0 x body mass and leg press ≥ 3.0 x body mass to be eligible.
  • Regular caffeine consumption (due to the presence of caffeine in the commercially available dietary supplement). This will be defined as an average self-reported daily intake of 250+ mg of caffeine, which is equivalent to approximately 2.5 cups of coffee.
Exclusion Criteria
  • Failing to meet any of the aforementioned inclusion criteria.
  • Pregnant or breastfeeding (for female participants)
  • Taking prescription medication which could reasonably make participation unsafe for the participant or influence study outcomes
  • An inability to complete resistance exercise due to injury or medical condition
  • Self-reported caffeine sensitivity, as indicated by unwanted side effects when caffeine is consumed.
  • Allergy to any of the ingredients in the test beverages or standardized breakfast.
  • Current use of anabolic steroids
  • Presence of a pacemaker or other implanted electrical device.
  • Unwillingness to wear the provided surgical mask during all testing procedures.

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
Caffeinated Pre-workout SupplementCaffeinated pre-workout supplementThis arm will consist of ingestion of the commercially available, caffeinated Pulse pre-workout, manufactured by Legion Athletics, Inc.
Non-Caffeinated Pre-Workout SupplementNon-caffeinated pre-workout supplementThis arm will consist of ingestion of the commercially available, non-caffeinated Pulse pre-workout, manufactured by Legion Athletics, Inc.
PlaceboPlaceboThis arm will consist of a flavor-matched placebo beverage without the active components contained in the supplements administered in the other study arms.
Primary Outcome Measures
NameTimeMethod
Isometric Peak Force ProductionApproximately 35 minutes after beverage ingestion in each condition.

Peak isometric force produced on a mechanical squat device at an 120-degree knee angle.

Isokinetic Peak Concentric Force ProductionApproximately 40 minutes after beverage ingestion in each condition.

Peak concentric force produced during isokinetic testing on a mechanical squat device.

Maximal Strength on Leg Press ExerciseApproximately 95 minutes after beverage ingestion in each condition.

One-repetition maximum for the plate-loaded leg press exercise.

Isometric Rate of Force DevelopmentApproximately 35 minutes after beverage ingestion in each condition.

Rate of force development produced on a mechanical squat device at an 120-degree knee angle.

Isokinetic Peak Eccentric Force ProductionApproximately 40 minutes after beverage ingestion in each condition.

Peak eccentric force produced during isokinetic testing on a mechanical squat device.

Maximal Strength on Bench Press ExerciseApproximately 65 minutes after beverage ingestion in each condition.

One-repetition maximum for the barbell bench press exercise.

Muscular Endurance on Bench Press ExerciseApproximately 70 minutes after beverage ingestion in each condition.

Repetitions to failure on the bench press exercise, using a load corresponding to 0.4 times body mass for females and 0.75 times body mass for males.

Muscular Endurance on Leg Press ExerciseApproximately 100 minutes after beverage ingestion in each condition.

Repetitions to failure on the leg press exercise, using a load corresponding to 1.5 times body mass for females and 2.5 times body mass for males.

Secondary Outcome Measures
NameTimeMethod
Subjective Ratings of EnergyFive total assessments in each condition. Immediately prior to: beverage ingestion, isometric exercise testing, bench press testing, and leg press testing. Also, immediately after leg press testing.

Subjective rating of energy as indicated by visual analog scale (0 to 100, with a higher value indicating a higher rating of energy).

Subjective Ratings of FocusFive total assessments in each condition. Immediately prior to: beverage ingestion, isometric exercise testing, bench press testing, and leg press testing. Also, immediately after leg press testing.

Subjective rating of focus as indicated by visual analog scale (0 to 100, with a higher value indicating a higher rating of focus).

Subjective Ratings of FatigueFive total assessments in each condition. Immediately prior to: beverage ingestion, isometric exercise testing, bench press testing, and leg press testing. Also, immediately after leg press testing.

Subjective rating of fatigue as indicated by visual analog scale (0 to 100, with a higher value indicating a higher rating of fatigue).

Trial Locations

Locations (1)

Department of Kinesiology & Sport Management

🇺🇸

Lubbock, Texas, United States

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