Prediction of Recurrent Events with 18F-Fluoride to Identify Ruptured and High-risk Coronary Artery Plaques in Patients with Myocardial Infarction - the PREFFIR study - PREFFIR - Prediction of Recurrent Events With 18F-Fluoride

niversity of Edinburgh0 个研究点目标入组 700 人开始时间: 2015年4月21日最近更新: 2020年4月20日

适应症

试验速览

暂无简介。

•1.Patients aged =50 years with recent (<21 days) type 1 myocardial infarction and angiographically proven multi-vessel coronary artery disease defined as at least two major epicardial vessels with any combination of either (a) >50% luminal stenosis, or (b) previous revascularization (percutaneous coronary intervention or coronary artery bypass graft surgery).
•2.Provision of informed consent prior to any study specific procedures
•Are the trial subjects under 18? no
•Number of subjects for this age range: 0
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 300
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 400

•1. Inability or unwilling to give informed consent
•2.Women who are pregnant, breastfeeding or of child-bearing potential (women who have experienced menarche, are pre-menopausal and have not been sterilised) will not be enrolled into the trial
•3.Major intercurrent illness with life expectancy <2 year
•4.Renal dysfunction (estimated glomerular filtration rate =30 mL/min/1.73 m2)
•5.Contraindication to iodinated contrast agent, positron emission tomography or computed tomography
•6.Permanent or persistent atrial fibrillation
•7.Previous screening as part of the trial

发起方

niversity of Edinburgh