Analysis of the Incidence and Risk Factors of Chronic Pain After Cesarean Section
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Postoperative Pain
- Sponsor
- Huazhong University of Science and Technology
- Enrollment
- 600
- Locations
- 1
- Primary Endpoint
- Incidence of chronic pain after caesarean section
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
Persistent postoperative pain is a globally recognized issue that deserves attention. Cesarean section is one of the surgeries that may cause persistent postoperative pain. PSPP may affect communication between mother and baby, and may lead to postpartum depression, which has a negative impact on the daily activities and quality of life of mothers. It is an important clinical issue.
The main purpose of this study is to (1) prospectively investigate the overall incidence and characteristics of persistent pain after cesarean section at 3, 6, and 12 months after surgery; (2) Use regression analysis and data modeling analysis to evaluate the relationship between perioperative variables and chronic pain in postpartum women undergoing cesarean section; (3) Analyze the relationship between chronic pain after cesarean section and postpartum depression in postpartum women.
Investigators
Xianwei Zhang，MD
Professor
Huazhong University of Science and Technology
Eligibility Criteria
Inclusion Criteria
- •Age range from 20 to 50 years old;
- •ASA grades I to III;
- •Full term pregnancy and planned cesarean section with transverse incision in the lower segment of the uterus;
- •Pregnant women who are willing to participate in this study and sign informed consent forms.
Exclusion Criteria
- •Have a history of dementia, mental illness, or any central nervous system disorder;
- •Pregnant women who are addicted to alcohol and drugs;
- •Difficulty in follow-up or poor patient compliance;
- •Has taken other investigational drugs or participated in other clinical trials in the three months prior to being selected for the study;
- •Serious complications occur during delivery;
- •Unable to cooperate with the research for any reason.
Outcomes
Primary Outcomes
Incidence of chronic pain after caesarean section
Time Frame: 2024-01-01-2025-01-01
Assessment of chronic postoperative pain by Brief Pain Inventory from 0 to ten, The higher the score, the stronger the pain
Secondary Outcomes
- Identification of high-risk factors for postoperative inadequate analgesia and PONV in obstetric patients based on machine learning methods(2024-2026)
- Adverse effects of postoperative analgesia(2024-2026)
- Checklist for Chronic pain after cesarean section(2024-2026)