Community Acquired Sepsis Cohort

Terminated

• Conditions: Severe Septic Syndrome; Septic Shock

• Registration Number: NCT03280992
• Lead Sponsor: Rennes University Hospital

Brief Summary

The aim of this project is to constitute a prospective cohort of all the patients presenting to the adult emergencies of the University Hospital Centre (CHU) of Rennes for a septic syndrome of community origin.

Detailed Description

Severe septic syndrome (SSG) and septic shock (CS) are two frequent and serious complications of infectious diseases. In this context, the optimization of the management of septic patients from their reception in the emergency services must be a priority. However there are no predictors of progression or severity in patients admitted to emergencies despite the recommendations emphasizing the need for screening and early therapeutic management. Many scores have been proposed for intensive care unit but they remain difficult to extrapolate to other services because they are very comprehensive and require information that is difficult to obtain for emergency physicians.

Study Timeline

• Study Start: 2016-03-02
• Study First Submitted: 2017-08-18
• Study First Submitted QC: 2017-09-12
• Study First Posted: 2017-09-13
• Primary Completion: 2018-08-27
• Study Completion: 2018-08-27
• Status Verified: 2021-12
• Last Update Submitted: 2021-12-01
• Last Update Posted: 2021-12-02

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 796

Inclusion Criteria

• Patient older than 18 years old
• Patient hospitalized during the study period for community infectious diseases at the CHU of Rennes

Exclusion Criteria

• Written objection from the patient to the computer processing of his data
• Pregnant women
• Persons subject to major legal protection (safeguarding justice, guardianship, trusteeship), persons deprived of liberty

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Internal validity, triage score by orientation nurses	Day 90
Internal validity, severity score	Day 90
Study of the prognostic factors of patients with septic syndrome of community origin in terms of mortality	Day 90
Assessment of morbidity in patients with septic syndrome of community origin	Day 90	Study of prognostic factors

Trial Locations

Locations (1)

CHU de Rennes; 🇫🇷 Rennes, France