Efficacy of Nasal high frequency oscillatory ventilation (nHFOV) VERSUS Synchronised non-invasive positive pressure ventilation (SNIPPV) VERSUS Nonsynchronised non-invasive positive pressure ventilation (NS-NIPPV) as a post extubation respiratory support in preterm neonates (≥ 28 WEEKS OF GESTATION) admitted in a tertiary care centre – A 3 ARM RANDOMIZED CONTROL TRIAL

We hypothesize that nHFOV, SNIPPV & NS-NIPPV are equally efficacious as a mode of respiratory support after extubation & reduce the need for endotracheal re-intubation. Comparison of nHFOV with NIPPV is still in its infancy and more studies are required to come to a consensus statement. In this study we have planned to compare nHFOV versus SNIPPV versus NS-NIPPV as a post extubation respiratory mode in preterm neonates more than equal to 28 weeks of gestational age admitted in a tertiary care centre from eastern India which to the best of our knowledge has not been done so far.