NL-OMON51610尚未招募不适用
Sex differences in the acute effects of guanfacine on activation of the brain stress system in individuals with an alcohol use disorder - SANE-study (Sex-differences, alcohol misuse and Negative Emotions)
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •- Meeting at least 2 of the 11-DSM5 criteria for alcohol use disorder
- •- age 25-45
排除标准
- •- MRI contraindications
- •- having a cardiovascular disease
- •- the presence of cardiovascular risk factors (a history of sudden fainting
- •without reason, a relative that died as a consequence of heart failure before
- •the age of 60, a relative with pacemaker)
- •- heartrate < 60, systolic blood pressure < 120 on the day of testing
- •- the use of psychotropic medication (e.g., Ritalin, SSRI's, medication acting
- •on cardiovascular system; The use of CYP3A4-inductors and inhibitors)
- •- a history of neurological disorders
- •- for women: being pregnant, or breastfeeding
- •- An indication of a substance use disorder other than alcohol use disorder
- •based on the drug use disorder identification test (exclusion when score is
- •higher than 11)
- •- smoking more than 10 cigarettes per day
- •- a positive alcohol breath test on the day of testing
- •BMI < 18 or > 30
研究者
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