Nanofat Versus Platelet Poor Plasma Gel for Infraorbital Rejuvenation

Phase 1

Completed

• Conditions: Tear Trough Eyelid Deformity
• Interventions: Biological: platelet poor plasma gel; Biological: nanofat

• Registration Number: NCT06318091
• Lead Sponsor: Mansoura University

Brief Summary

this study was conducted for evaluation of the clinical efficacy, safety, and potential side effects of platelet poor plasma gel versus nonfat injection in infraorbital rejuvenation

Detailed Description

Not available

Study Timeline

• Study Start: 2021-06-01
• Primary Completion: 2023-06-01
• Study Completion: 2023-06-01
• Status Verified: 2024-03
• Study First Submitted: 2024-03-05
• Study First Submitted QC: 2024-03-12
• Last Update Submitted: 2024-03-12
• Study First Posted: 2024-03-19
• Last Update Posted: 2024-03-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• all patients with infraorbital dark circles

Exclusion Criteria

• pregnancy
• breast feeding
• infectious disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
platelet poor plasma gel group	platelet poor plasma gel	in this group, plasma gel will be injected intradermally in the dark circles.
nanofat group	nanofat	in this group, nanofat will be injected intradermally and subcutaneously in the dark circles

Primary Outcome Measures

Name	Time	Method
the degree of changes in the skin texture and homogeneity	3 months	the degree of changes in the skin texture and homogeneity was assessed using the five grades scale according to percentage of change in skin surface smoothness and color uniformity (1: much worse if deterioration \>25%, 2: worse if deterioration \<25%, 3: slightly improved if improvement \<25%, 4: improved if improvement = 25%-50%, and 5: greatly improved if improvement \>50%).

Trial Locations

Locations (1)

Manousra University, Faculty of Medicine; 🇪🇬 Mansoura, Dakahlia, Egypt