MedPath

Influence of Expiration Lente Prolongée on Gastro-oesophageal Reflux

Not Applicable
Completed
Conditions
Gastro-esophageal Reflux
Interventions
Other: expiration lente prolongée
Registration Number
NCT03341585
Lead Sponsor
Vrije Universiteit Brussel
Brief Summary

The purpose of this study is to determine whether a specific airway clearance technique, l'Expiration Lente Prolongée (ELPr), induces or aggravates gastro-oesophageal reflux in infants under the age of one year. Infants referred to hospital for a multichannel intraluminal impedance pH (pH-MII) monitoring are included in this study. Participation is only possible after signing the informal consent by one of the parents.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
55
Inclusion Criteria
  • Infants under the age of one year and on suspicion of GOR who were referred for 24h impedance-pH monitoring are included in this study.
Exclusion Criteria
  • prematurity (gestational age less than 37 weeks),
  • the use of anti-reflux medication and reflux surgery (Nissen fundoplication)

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Expiration Lente Prolongéeexpiration lente prolongéeIn this controlled trial with intra-subject design infants will be studied using multichannel intraluminal impedance pH (pH-MII) monitoring , during which they receive one 20 min session of 'Expiration Lente Prolongée (ELPr)' . The number of reflux episodes (RE) is the outcome measure. The results obtained during and 20 min after the intervention will be compared to a period of 20 min before treatment ( control ).
Primary Outcome Measures
NameTimeMethod
number of refluxes20 minutes
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

UZ Brussel

🇧🇪

Jette, Brussels, Belgium

© Copyright 2025. All Rights Reserved by MedPath