CTRI/2020/07/026712进行中（未招募）未知
Withdrawal of maintenance glucocorticoid versus other immunosuppressants among patients with Systemic Lupus Erythematosus in long term clinical remission : a Non-inferiority Randomised Controlled Trial
试验速览
- 阶段
- 未知
- 状态
- 进行中（未招募）
- 发起方
- JIPMER
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •i. Patients classified as Systemic Lupus Erythematosus(SLE) according to Systemic Lupus International Collaborating Clinic criteria for the classification of SLE (SLICC criteria).
- •ii. Age 18 years or above
- •iii. At least 3 years of total treatment and 1 year of complete remission before withdrawing treatment and on stable dose of prednisolone/immunosuppressant.
- •Remission of SLE defined as per DORIS consensus (Remission on therapy allows patients to be treated with maintenance antimalarial, stable, low-dose glucocorticoids, maintenance immunosuppressants and/or stable (maintenance) biologics
排除标准
- •i.Pregnancy or women in the reproductive age group who have not yet completed family and not willing for contraception as required.
- •ii.Patients with estimated Glomerular Filtration Rate (eGFR) < 60ml/min/m2
- •iii.Renal biopsy at remission showing histological activity score >4/24 or presence of crescents
研究者
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