Comparison of Onset, duration, quality of postoperative analgesia of epidurally administered Bupivacaine with Dexmedetomidine group and Bupivacaine with Buprenorphine group.

Not yet recruiting

• Conditions: Bilateral primary osteoarthritis of knee,

• Registration Number: CTRI/2023/10/058865
• Lead Sponsor: vydehi institute of medical sciences

Brief Summary

epidural anesthesia is the most commonly used technique for providing not only intraoperative surgical anesthesia but also postoperative analgesia in lower abdominal and lower limb surgeries. early postoperative mobilization and rehabilitation with minimally associated pain and discomfort is the most desirable feature in modern orthopedic surgery. epidural analgesia also obtunds cental sensitizationn and pain induced organ dysfunction, leading to improved outcome.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-10-18
• Study Start: 2023-10-31

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 126

Inclusion Criteria

1)ASA 1 & 2 2)PATIENTS UNDERGOING TOTAL KNEE AND HIP REPLACEMENT SURGERIES 3)Uneventful intraoperative patients.

Exclusion Criteria

1)ASA 3 & 4 2)ALLERGY TO LOCAL ANESTHETICS, DEXMEDETOMIDINE AND BUPRENORPHINE 3) BLEEDING AND NEUROMUSCULAR DISORDERS.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare onset, duration, quality of postoperative analgesia of epidurally administered bupivacaine with dexmedetomidine and bupivacaine with buorenorphine	To compare onset, duration, quality of postoperative analgesia of epidurally administered bupivacaine with dexmedetomidine and bupivacaine with buorenorphine

Secondary Outcome Measures

Name	Time	Method
assess and compare the haemodynamic parameters, side effects and time for ambulation	after giving epidural topup onset of analgesia, sedation, duration of analgesia, haemodynamic parameters, mobilization time

Trial Locations

Locations (1)

Vydehi Institute of Medical sciences And Research centre; 🇮🇳 Bangalore, KARNATAKA, India

Vydehi Institute of Medical sciences And Research centre

🇮🇳Bangalore, KARNATAKA, India

DrMeenakshi T

Principal investigator

8073744059

mnksh97@gmail.com