Effects of Volume and Pressure-Controlled Ventilation on Cerebral SpO2, PI, and PVI Index in Septoplasty

Completed

• Conditions: Ventilation Mode; Pleth Variability Index; Perfusion Index; Regional Cerebral Oxygen Saturation
• Interventions: Diagnostic Test: Cerebral Oxygen Saturation

• Registration Number: NCT06407362
• Lead Sponsor: Sanliurfa Mehmet Akif Inan Education and Research Hospital

Brief Summary

Objective: This study was designed to evaluate the accuracy of Pleth Variability Index (PVI), Perfusion Index (PI) and Regional Oxygen Saturation (rSO2) in both ventilation modes in patients undergoing septorhinoplasty operation under general anaesthesia. Materials and Methods: After anaesthesia induction, ventilation was provided with volume control for 20 minutes. Heart Rate (HR), PI, PVI, Oxygen Saturation (SpO2), Non-Invasive Blood Pressure (NIBP) and rSO2 values were recorded every 5 minutes. At the 20th minute of the surgical procedure, the ventilation mode was set as the pressure-controlled mode. After switching to pressure-controlled mode, HR, PI, PVI, SpO2, NIBP and rSO2 values were recorded every 5 minutes for 20 minutes.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-05-15
• Primary Completion: 2023-01-15
• Study Completion: 2023-01-15
• Status Verified: 2024-05
• Study First Submitted: 2024-05-02
• Study First Submitted QC: 2024-05-06
• Last Update Submitted: 2024-05-06
• Study First Posted: 2024-05-09
• Last Update Posted: 2024-05-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• patients with American Society of Anesthesiologists (ASA) score I-III between the ages of 18-80 were included

Exclusion Criteria

• Those patients with any Liver and/or Kidney Failure
• obese patients (Body Mass Index (BMI) 30 and above)
• trauma patients
• cancer patients
• ASA IV patients
• those patients with emergency surgery
• cardiac arrhythmia
• implanted pacemakers
• those with a history of chronic pain

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients who had undergone septoplasty	Cerebral Oxygen Saturation	-

Primary Outcome Measures

Name	Time	Method
Regional Cerebral Oxygen Saturation (rSO2) in patients under different ventilation modes	while the surgery procedure	The objective of this study was to demonstrate the percentage difference in the Regional Cerebral Oxygen Saturation (rSO2) between the two ventilation modes in patients undergoing septorhinoplasty.
Perfusion Index (PI) in patients under different ventilation modes	while the surgery procedure	The objective of this study was to demonstrate the percentage difference in the Perfusion Index (PI) between the two ventilation modes in patients undergoing septorhinoplasty.
Pleth Variability Index (PVI) in patients under different ventilation modes	while the surgery procedure	The objective of this study was to demonstrate the percentage difference in the Pleth Variability Index (PVI) between the two ventilation modes in patients undergoing septorhinoplasty.

Trial Locations

Locations (1)

University of Health Science Turkey Sanliurfa Mehmet Akif Inan Training and Research Hospital; 🇹🇷 Şanlıurfa, Turkey