NL-OMON38169已完成不适用
Phenylephrine versus EPhedrine on cerebral Perfusion during Carotid EndarteRectomy - PEPPER trial
niversitair Medisch Centrum Utrecht0 个研究点目标入组 40 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •To be included in the current study all patients must meet the following criteria:
- •1. Undergoing CEA because of a symptomatic high degree stenosis of the ICA in the University Medical Centre Utrecht
- •2. Having an appropriate temporal bone window for reliable perioperative TCD monitoring
- •3. Have given written informed consent.
- •4. A decrease in MAP >20%
排除标准
- •Exclusion criteria
- •Patients will be excluded if they meet one of the following criteria:
- •1. Not having a temporal bone window appropriate for TCD measurement
- •2. Not willing to give informed consent.
- •3. No decrease in MAP >20%
- •4. A heart rate less than 50 beats per minute at the time of administration.
- •5. Hypersensitivity to either ephedrine of phenylephrine
研究者
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The effect of blood pressure changes in blood pressure on cerebral perfusion during carotid surgeryHypotension during carotid endarterectomyMedDRA version: 14.1Level: PTClassification code 10062300Term: Procedural hypotensionSystem Organ Class: 10022117 - Injury, poisoning and procedural complicationsMedDRA version: 14.1Level: PTClassification code 10007692Term: Carotid endarterectomySystem Organ Class: 10042613 - Surgical and medical proceduresEUCTR2011-003470-88-NLniversity Medical Center Utrecht, The Netherlands
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