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Promoting Safety Plan and Coping Strategy Use Among Adults With Suicidal Thoughts

Not Applicable
Recruiting
Conditions
Suicide
Interventions
Behavioral: Personalized internal and external coping strategies
Behavioral: Personalized internal coping strategies
Behavioral: Personalized external coping strategies
Behavioral: General internal and external coping strategies
Behavioral: General internal coping strategies
Behavioral: General external coping strategies
Behavioral: General internal coping strategies, relaxation
Behavioral: General internal coping strategies, distraction
Behavioral: General internal coping strategies, physical activity
Registration Number
NCT05791643
Lead Sponsor
Massachusetts General Hospital
Brief Summary

The goal of this study is to learn about a new, real-time, smartphone-based intervention aimed to decrease risk for suicide in adults who have been hospitalized for suicidal thoughts or behaviors. The main questions the investigators aim to answer are:

* Is a real-time, smartphone-based intervention that promotes the use of safety plans and other coping strategies for suicidal thoughts feasible and acceptable?

* Does the real-time intervention result in increased use of safety plans and other coping strategies, and reduce suicidal thoughts?

Participants will:

* Answer questions about current suicidal thoughts on their smartphone up to 6 times each day while they are in the hospital and during the 4 weeks after they leave the hospital

* When they report elevated suicidal thoughts on a smartphone survey, be randomly assigned to receive or not receive automated, interactive reminders to use content from their personalized safety plan or general coping strategies

* Answer brief follow-up questions on their smartphone within a couple hours of receiving or not receiving automated reminders

* Give feedback on their experience with the real-time intervention

Detailed Description

Effective, scalable interventions for the highest-risk time for suicide - after inpatient psychiatric hospitalization - are urgently needed. The safety planning intervention (Stanley \& Brown, 2012) involves developing a personalized list of prioritized coping strategies for suicidal crises, and has been shown to prevent suicidal behavior (e.g., Nuij et al., 2021). However, roughly 40% of patients with a safety plan never use it (Stanley et al., 2016). The safety plan also includes multiple components (e.g., different internal coping strategies, seeking social support), yet little is known about the internal and external contexts that may impact the accessibility and effectiveness of individual safety plan components. Improving both the ability to promote safety plan use when needed and the understanding of when specific coping strategies are most accessible and effective has the potential to optimize this already evidence-based intervention.

The aim of this study is to leverage the recent micro-randomized trial (MRT) design (Klasnja et al., 2015) to evaluate the proximal effects of automated, interactive, smartphone-based reminders to implement the safety plan and its coping strategies at different levels of suicidal urges and intent. Twenty-five (N = 25) adults hospitalized for suicidal thoughts or behaviors will undergo an intensive longitudinal monitoring protocol, which includes completing up to six brief smartphone surveys per day that assess momentary suicidal urges and intent on a 0 to 10 scale during hospitalization and the 28 days after discharge. After each post-discharge survey with reported high intensity suicidal urges or moderate intent, participants will be "micro-randomized" to receive either a series of automated interactive intervention messages or no intervention. Whether the message content is personalized (from the individual's safety plan) or general (top-rated from others' safety plans) and the specific coping strategy type(s) recommended will also be randomized. Brief proximal follow-up surveys will assess coping strategy use since the last survey prompting micro-randomization, perceived helpfulness of any coping strategies used, and momentary suicidal urges and intent. Qualitative and quantitative data on acceptability and feasibility will be collected from participants and used to inform future real-time intervention refinements. Preliminary efficacy data will be used to inform the development of future, larger-scale studies and the ultimate development of policies for novel just-in-time adaptive interventions that deliver the right time of support, at the right time, and in the right context, for individuals at risk for suicide.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
25
Inclusion Criteria
  • Experiencing suicidal thoughts as part of their inpatient admission
  • Ownership of and access to a smartphone (while on the unit and following discharge)
  • Ability to speak and write English fluently
Exclusion Criteria
  • Any factor that impairs the ability to effectively participate in the study (e.g., significant cognitive impairment, intellectual disability, presence of violent behavior, psychotic illness/symptoms determined by the treating clinician to impair ability to understand the study or provide informed consent)
  • Failure to correctly answer all true/false questions in the consent form

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Real-time intervention for promoting safety plan and coping strategy useGeneral internal coping strategies, relaxationMomentary surveys in which elevated (non-zero but \< 8 out of 10) levels of suicidal intent or high (\>= 8 out of 10) suicidal urges are reported will be randomized either to receive a real-time intervention that consists of automated, interactive reminders with suggested strategies for coping with suicidal thoughts or no intervention. If randomized to receive an intervention, the intervention type will also be randomized (at equal probabilities) to suggest either coping strategies from the participant's personalized safety plan or general common coping strategies.
Real-time intervention for promoting safety plan and coping strategy usePersonalized internal and external coping strategiesMomentary surveys in which elevated (non-zero but \< 8 out of 10) levels of suicidal intent or high (\>= 8 out of 10) suicidal urges are reported will be randomized either to receive a real-time intervention that consists of automated, interactive reminders with suggested strategies for coping with suicidal thoughts or no intervention. If randomized to receive an intervention, the intervention type will also be randomized (at equal probabilities) to suggest either coping strategies from the participant's personalized safety plan or general common coping strategies.
Real-time intervention for promoting safety plan and coping strategy usePersonalized external coping strategiesMomentary surveys in which elevated (non-zero but \< 8 out of 10) levels of suicidal intent or high (\>= 8 out of 10) suicidal urges are reported will be randomized either to receive a real-time intervention that consists of automated, interactive reminders with suggested strategies for coping with suicidal thoughts or no intervention. If randomized to receive an intervention, the intervention type will also be randomized (at equal probabilities) to suggest either coping strategies from the participant's personalized safety plan or general common coping strategies.
Real-time intervention for promoting safety plan and coping strategy useGeneral external coping strategiesMomentary surveys in which elevated (non-zero but \< 8 out of 10) levels of suicidal intent or high (\>= 8 out of 10) suicidal urges are reported will be randomized either to receive a real-time intervention that consists of automated, interactive reminders with suggested strategies for coping with suicidal thoughts or no intervention. If randomized to receive an intervention, the intervention type will also be randomized (at equal probabilities) to suggest either coping strategies from the participant's personalized safety plan or general common coping strategies.
Real-time intervention for promoting safety plan and coping strategy usePersonalized internal coping strategiesMomentary surveys in which elevated (non-zero but \< 8 out of 10) levels of suicidal intent or high (\>= 8 out of 10) suicidal urges are reported will be randomized either to receive a real-time intervention that consists of automated, interactive reminders with suggested strategies for coping with suicidal thoughts or no intervention. If randomized to receive an intervention, the intervention type will also be randomized (at equal probabilities) to suggest either coping strategies from the participant's personalized safety plan or general common coping strategies.
Real-time intervention for promoting safety plan and coping strategy useGeneral internal and external coping strategiesMomentary surveys in which elevated (non-zero but \< 8 out of 10) levels of suicidal intent or high (\>= 8 out of 10) suicidal urges are reported will be randomized either to receive a real-time intervention that consists of automated, interactive reminders with suggested strategies for coping with suicidal thoughts or no intervention. If randomized to receive an intervention, the intervention type will also be randomized (at equal probabilities) to suggest either coping strategies from the participant's personalized safety plan or general common coping strategies.
Real-time intervention for promoting safety plan and coping strategy useGeneral internal coping strategiesMomentary surveys in which elevated (non-zero but \< 8 out of 10) levels of suicidal intent or high (\>= 8 out of 10) suicidal urges are reported will be randomized either to receive a real-time intervention that consists of automated, interactive reminders with suggested strategies for coping with suicidal thoughts or no intervention. If randomized to receive an intervention, the intervention type will also be randomized (at equal probabilities) to suggest either coping strategies from the participant's personalized safety plan or general common coping strategies.
Real-time intervention for promoting safety plan and coping strategy useGeneral internal coping strategies, physical activityMomentary surveys in which elevated (non-zero but \< 8 out of 10) levels of suicidal intent or high (\>= 8 out of 10) suicidal urges are reported will be randomized either to receive a real-time intervention that consists of automated, interactive reminders with suggested strategies for coping with suicidal thoughts or no intervention. If randomized to receive an intervention, the intervention type will also be randomized (at equal probabilities) to suggest either coping strategies from the participant's personalized safety plan or general common coping strategies.
Real-time intervention for promoting safety plan and coping strategy useGeneral internal coping strategies, distractionMomentary surveys in which elevated (non-zero but \< 8 out of 10) levels of suicidal intent or high (\>= 8 out of 10) suicidal urges are reported will be randomized either to receive a real-time intervention that consists of automated, interactive reminders with suggested strategies for coping with suicidal thoughts or no intervention. If randomized to receive an intervention, the intervention type will also be randomized (at equal probabilities) to suggest either coping strategies from the participant's personalized safety plan or general common coping strategies.
Primary Outcome Measures
NameTimeMethod
Intervention engagement as assessed by the number of real-time interventions received and percentage of real-time interventions completed4 weeks after hospital discharge

Engagement with the real-time intervention will be assessed by analyzing the total number interventions participants receive and the percentage of those received that they complete.

Extent to which the real-time intervention may be successfully used or implemented as assessed by the Feasibility of Intervention Measure4 weeks after hospital discharge

The extent to which the real-time intervention may be successfully used will be assessed by scoring and analyzing self-reported responses to the Feasibility of Intervention Measure.

Participant approval of the real-time intervention as assessed by the Acceptability of Intervention Measure4 weeks after hospital discharge

Participants' approval of the real-time intervention will be assessed by scoring and analyzing self-reported responses to the Acceptability of Intervention Measure.

Secondary Outcome Measures
NameTimeMethod
Self-reported safety plan and coping strategy useWithin two hours of each micro-randomization

Participants may be prompted within two hours of each micro-randomization to complete a brief follow-up smartphone survey that assesses safety plan and/or coping strategy use since the initial survey prompting micro-randomization.

Self-reported momentary suicidal urges and intentWithin two hours of each micro-randomization

Participants may be prompted within two hours of each micro-randomization to complete a brief follow-up smartphone survey that assesses momentary suicidal urge and intent (on a 0 to 10 scale).

Trial Locations

Locations (2)

McLean Hospital

🇺🇸

Belmont, Massachusetts, United States

Massachusetts General Hospital

🇺🇸

Boston, Massachusetts, United States

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