IRCT20181225042116N1招募中2 期
Comparison effects of Itraconazole and Prednisone on Fibroblast Growth Factor 2 gene expression, clinical manifestation and other tests in patients with persistent severe asthma
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 70
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 no limit（—）
- 性别
- All
入选标准
- •Age older than 18 years old
- •No response to high dose inhaled corticosteroids and long acting beta agonist with antileukotriene
- •Forced expiratory volume in one second less than 80 percent
- •Fungal sensitization
排除标准
- •Sensitivity and drug interaction with Itraconazole
- •History of taking Itraconazole
- •Gastroesophageal reflux disease Known and untreated
- •Severe heart disease
- •Known liver and kidney disease
- •Chronic eosinophilic pneumonia
- •Charge Strauss syndrome
- •Chronic Obstructive Pulmonary Disease
- •Total IgE more than 1000IU/ml
- •Pregnancy or breastfeeding
- •Lack of access to Appropriate RNA in patient sputum sample
- •Sarcoidosis
- •Hypersensitivity pneumonitis
- •Impaired vocal cords
- •Central airway obstruction
- •Sleep apnea
研究者
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