The effect of Scaling and Root Planning on level of TNF-alpha and IL-1alpha of saliva
Not Applicable
- Conditions
- Chronic Periodontitis.chronic periodontitis
- Registration Number
- IRCT2016052825649N3
- Lead Sponsor
- Vice Chancellor for research of Kermanshah University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Inclusion criteria : Subjects with chronic periodontitis; Subjects with periodonta healthy; being healthy.
Exclusion criteria : Subjects with systemic disorders (e.g.,diabetes mellitus, asthma); Pregnancy and Lactation; Having Less than 20 teeth; Use of antibiotics during last month; History of continuous consumption of NSATDs; Smoking , Alcohol abuse; History of periodontal treatments during one previous year; Subjects with inflammatory mucosal lesions (Lichen Planus) and Salivary gland disease
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Interleukin-1alpha. Timepoint: At the time of scaling and 30 days after it. Method of measurement: ELISA kit.;Tumor Necrosis Factor alpha. Timepoint: At the time of scaling and 30 days later. Method of measurement: ELISA kit.
- Secondary Outcome Measures
Name Time Method Pocket depth. Timepoint: At the time of scaling and 30 days later. Method of measurement: measuring the distance of pocket base to the gingval margin using periodontal probe.;Clinical Attachment Loss. Timepoint: At the time of scaling and 30 days later. Method of measurement: measuring the distance of base of the pocket from CEJ.;Bleeding during Probing. Timepoint: At the time of scaling and 30 days later. Method of measurement: Observation.;Plaque Index. Timepoint: At the time of scaling and 30 days later. Method of measurement: Observation.