Effect of fasting versus bedtime levothyroxin on primary hypothyroidism
Phase 2
- Conditions
- primary hypothyroidism.Hypothyroidism, unspecified
- Registration Number
- IRCT201406299014N38
- Lead Sponsor
- Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
(a) patients with primary hypothyroiditis; (b) age of 18 years or older.
Exclusion criteria: (a) history of cardiovascular disease; (b) being pregnant or plan to pregnant; (c) history of malabsorption or gastritis; (d) using drug reducing levothyroxine absorption such as aluminum or sucralfate.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Response to treatment. Timepoint: 8 months after treatment. Method of measurement: based on serum T4 level.;Response to treatment. Timepoint: 8 months after treatment. Method of measurement: based on serum TSH level.
- Secondary Outcome Measures
Name Time Method Probable systematic adverse effects such as nausea and vomiting. Timepoint: 8 months after treatment. Method of measurement: through history taking.