The alteration of metabolites and clinical correlation in cerebral aneurysm induced subarachnoid hemorrhage patients, a pilot study.

• Conditions: Subarachnoid hemorrhage with ruptured intracranial aneurysm and non-ruptured intracranial aneurysm; subarachnoid hemorrhage, ruptured intracranial aneurysm, non-ruptured intracranial aneurysm, TNF-alpha, Metabolites, clinical outcomes

• Registration Number: TCTR20211029001
• Lead Sponsor: RESEARCH ADMINISTRATION DIVISION, KHON KEAN UNIVERSITY

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-10-29
• Study Completion: 2022-10-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

Non traumatic SAH with ventriculostomy at the aged above 18 years old

Exclusion Criteria

sepsis or other infected condition, pregnancy and not consent to study

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Metabolites and biomarkers Baseline Nuclear Magnetic Resonance (NMR) spectroscopy, ELISA

Secondary Outcome Measures

Name	Time	Method
Clinical outcomes Baseline and 1-month follow up Glasgow Coma Scale (GCS), World Federation of Neurosurgeons scale (WFNS) and Modified Ranking scale (mRS),Severity of SAH Baseline modified fisher scale,Association of metabolites, biomarker and clinical outcomes end of study Statistical analysis