The effect of Alpha lipoic acid supplementation on male infertility
Phase 2
- Conditions
- Asthenospermia.male infertility
- Registration Number
- IRCT2013111010181N3
- Lead Sponsor
- Ahvaz Jundishapur University of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 40
Inclusion Criteria
Willing to participate in the study and filling out the informed consent form; they should be infertile (no conception after 12 months intercourse without any contraception); age 20-45 y.o; idiopathic asthenospermia according to WHO criteria; normal hormonal profile.
Exclusion criteria: any infection in genitourinary (GU) tract; any anatomical abnormality in GU tract; any chronic disease during last 3 months; any surgery in GU tract; consumption of antioxidant supplements during last 3 months.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sperm motility. Timepoint: 12 weeks. Method of measurement: spermatogram.
- Secondary Outcome Measures
Name Time Method Gene expression and activity of Glutathione S-Transferase. Timepoint: 12 weeks. Method of measurement: Real Time-PCR- Spectrophotometric.