The effect of alpha-lipoic acid supplementation and Electrical isotonic contraction on Anthropometric parameters, body composition and Angiogenesis factor, sirtunin-1 andPGC1 a in obese people under weight loss regime

Phase 3

Recruiting

Conditions: Obesity.
Other obesity due to excess calories
E66.09

Registration Number: IRCT20131117015424N2

Lead Sponsor: Ahvaz University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 100

Inclusion Criteria

Body mass index is between 30-40 kg / m²
Age between 18-50
Lack of systemic, inflammatory and chronic diseases (diabetes, hypertension, kidney)
Lack of epilepsy
Non-use of anti-inflammatory drugs, hormones, weight loss drugs and antioxidant and vitamin supplements
Lack of Pregnancy and lactation
Not having skin problems and allergies
Not getting under a weight loss diet in the last 6 months
Failure to follow a particular diet
Lack of smoking and smoking

Exclusion Criteria

Systemic, inflammatory, liver, heart, kidney, and chronic diseases during the study
Pregnancy
Changes in diet and physical activity
Unwillingness to cooperate

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
VEGF Angiogenesis Factor. Timepoint: The beginning and the end of the study. Method of measurement: With ELISA method.;NO Concentration. Timepoint: The beginning and the end of the study. Method of measurement: With ELISA method.;Sirtoin Concentration. Timepoint: The beginning and the end of the study. Method of measurement: With ELISA method.;PGC1a Concentrations. Timepoint: The beginning and the end of the study. Method of measurement: With ELISA method.

Secondary Outcome Measures

Name	Time	Method
Weight. Timepoint: The beginning and the end of the study. Method of measurement: Scales.;Waist. Timepoint: The beginning and the end of the study. Method of measurement: Meter.;Body Mass Index. Timepoint: The beginning and the end of the study. Method of measurement: Computing.;Body Slim Percentage. Timepoint: The beginning and the end of the study. Method of measurement: BIA machine.;Body Fat Percentage. Timepoint: The beginning and the end of the study. Method of measurement: BIA machine.