Using Short Message Service as a Means of Clinical Engagement in Early Psychosis

Not Applicable

Completed

• Conditions: Psychotic Disorders

• Registration Number: NCT04379349
• Lead Sponsor: Centre for Addiction and Mental Health

Brief Summary

Engagement with clinical services for youth with early psychosis represents a significant challenge, with up to 40% of patients dropping out of treatment in the first year. This has been linked to worse illness outcomes and represents a significant barrier to recovery for these patients. This study aims to evaluate the efficacy of short message service (SMS) as a means of improving clinical engagement in early-episode psychosis populations by bridging contact between appointments with weekly check-ins/reminders. These weekly check-ins during the first year of treatment will serve as an additional opportunity to reach out to patients and give them a chance to do the same with their care teams, with patient responses triggering clinician follow-up if necessary.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-01
• Primary Completion: 2020-03-31
• Study Completion: 2020-03-31
• Status Verified: 2020-05
• Study First Submitted: 2020-05-05
• Study First Submitted QC: 2020-05-05
• Last Update Submitted: 2020-05-06
• Study First Posted: 2020-05-07
• Last Update Posted: 2020-05-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 61

Inclusion Criteria

• between the ages of 16-29
• a diagnosis of an affective or non-affective psychotic disorder (i.e., Bipolar or Major Depressive Disorders with Psychotic Features, Schizophrenia Spectrum Disorders, Other Specified Psychotic Disorders, Substance Induced Psychosis and Attenuated Psychotic Syndrome)
• eligible for follow-up within the Slaight Family Centre for Youth in Transition early intervention service
• within the first 6 months of treatment

Exclusion Criteria

• involved in another intervention study
• do not have a personal cell phone number

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Appointment Attendance	9 months	Percentage of attended clinic appointments
Service Engagement Scale (SES)	9 months	Clinician-rated treatment engagement and adherence (minimum score = 0, maximum score = 42, higher score indicates worse service engagement)

Secondary Outcome Measures

Name	Time	Method
Emergency Department Visits	9 months	Number of emergency department visits
Social Functioning Scale (SFS)	9 months	Self-report measure of social functioning (minimum score = 0, maximum score = 247, higher score indicates better functioning)
Clinical Global Impression (CGI)	9 months	Interview-based global rating of illness severity (minimum score = 1, maximum score = 7, higher score indicates worse illness severity)
Personal and Social Performance Scale (PSP)	9 months	Interview-rated measure of global functioning (minimum score = 1, maximum score = 100, higher score indicates better functioning)
Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LESQ-18)	9 months	Self-reported measure of subjective quality of life (minimum score = 1, maximum score = 5, higher score indicates better quality of life)
Scale for the Assessment of Negative Symptoms (SANS)	9 months	Interview-based measure of the severity of negative symptoms (minimum score = 0, maximum score = 110, higher score indicates higher severity of symptoms)
Brief Psychiatric Rating Scale (BPRS)	9 months	Interview-based measure of the severity of psychiatric symptoms (minimum score = 24, maximum score = 168, higher score indicates higher severity of symptoms)
Apathy Evaluation Scale (AES)	9 months	Interview-rated measure of the severity of motivation deficits (minimum score = 18, maximum score = 72, higher score indicates worse motivation deficits)
Brief Cognitive Assessment Tool for Schizophrenia (B-CATS)	9 months	Rater-administered measure of cognitive functioning (scores indicate standardized Z-scores with no pre-defined minimum or maximum score, higher score indicates better cognitive functioning)
Drug Attitude Inventory (DAI-10)	9 months	Self-reported measure of medication adherence (minimum score = -10, maximum score = + 10, higher score indicates better adherence)
Scale To Assess Therapeutic Relationships - Patient Version (STAR-P)	9 months	Self-reported measure of the clinician-patient therapeutic relationship (minimum score = 0, maximum score = 48, higher score indicates better therapeutic relationship)
Hospitalizations	9 months	Number of hospitalizations

Trial Locations

Locations (1)

Centre for Addiction and Mental Health; 🇨🇦 Toronto, Ontario, Canada