Effects of Virtual Reality Based Games in Rehabilitation of Parkinson's Disease

Not Applicable

Completed

• Conditions: Parkinson Disease
• Interventions: Other: Conventional exercises; Other: Virtual reality based games

• Registration Number: NCT05235880
• Lead Sponsor: Hacettepe University

Brief Summary

The purpose of this study is to investigate the effects of virtual reality based games on upper extremities, trunk and cognitive functions in patients with Parkinson's Disease.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study First Submitted: 2021-12-22
• Study First Submitted QC: 2022-02-02
• Study First Posted: 2022-02-11
• Study Start: 2022-04-15
• Primary Completion: 2023-06-15
• Study Completion: 2023-06-15
• Status Verified: 2023-09
• Last Update Submitted: 2023-09-20
• Last Update Posted: 2023-09-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Diagnosed with Parkinson's disease
• 50 years old and over
• Stage 1.5-3 according to the modified Hoehn-Yahr Staging Scale
• Mini mental test score of 24 and above

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Exclusion Criteria

• Additional neurological disease or symptom other than Parkinson's disease
• Orthopedic disorder that will prevent them from doing exercises
• Severe mental disorders

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
control group	Conventional exercises	1 hour physiotherapy session for 3 times a week and 8 weeks in total.
study group	Virtual reality based games	1 hour physiotherapy session for 3 times a week and 8 weeks in total.

Primary Outcome Measures

Name	Time	Method
Cognitive Status with Montreal Cognitive Assessment	Change from Baseline at 8 weeks	its validity and reliability in Turkish have been established. The total score ranges from 0-30, and a higher score indicates a better cognitive status. Below 21 points indicates cognitive impairment.
Upper extremities performance with Minnesota Manual Dexterity Test	Change from Baseline at 8 weeks	It involves taking small disc-shaped objects, each of standard size, to different distances on the table in the shortest possible time and placing them in sequence, while the patient is in a sitting position with a table in front of him/her.
Upper extremities performance with 9 hole peg test	Change from Baseline at 8 weeks	The patient sits with a table in front of him/her and places 9 small wooden sticks on the surface with nine holes on them, takes them out again and lays them on his/her side. He/she is asked to do it as quickly as possible and his/her time is saved
Trunk Functions with Trunk Impairment Scale	Change from Baseline at 8 weeks	It is a valid and reliable scale for evaluating the motor disorders and balance of the trunk in Parkinson's patients. The total score in the scale, which consists of 17 items in 3 sections, ranges from 0 to 23. A higher score indicates better trunk function and balance.

Secondary Outcome Measures

Name	Time	Method
Disease severity and symptoms with Unified Parkinson Disease Rating Scale Part 2 and 3	Change from Baseline at 8 weeks	It is one of the most frequently used scales to evaluate the severity of the disease in Parkinson's patients. It evaluates many problems such as motor and non-motor problems, treatment complications, problems in daily living activities and consists of 4 sections. However, in our study, the 2nd and 3rd sections which evaluate motor problems and activities of daily living will be used. Higher scores mean worse outcome.
Quality of life with Parkinson's Disease Questionnaire	Change from Baseline at 8 weeks	The 39-item Parkinson's Disease Questionnaire was developed to evaluate the quality of life of Parkinson's patients and has Turkish validity and reliability. Higher scores mean worse outcome.
Balance and mobility with Timed Up and Go Test	Change from Baseline at 8 weeks	While the patient is in a sitting position, he/she is asked to stand up from the chair, walk 3 meters, turn around, come back and sit down, and the time is recorded. Doing it in less time demonstrates better balance and mobility
Dynamic balance with functional reach test	Change from Baseline at 8 weeks	Functional reach test is frequently used to assess dynamic balance and fall risk. While the patient is standing by the wall, he/she raises his/her arm to 90 degrees and tries to reach as far as he/she can without taking his/her feet off the ground. Extending a longer distance indicates better balance and less risk of falling

Trial Locations

Locations (1)

Hacettepe University; 🇹🇷 Ankara, Turkey