Evaluation of the therapeutic efficiency of the placenta mesenchymal stem cell-derived exosomes on the improvement of interstitial lung
Not Applicable
Recruiting
- Conditions
- systemic sclerosis (scleroderma).Systemic sclerosis [scleroderma]
- Registration Number
- IRCT20130812014333N184
- Lead Sponsor
- Kermanshah University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
Informed consent
American College of Rheumatology (ACR) and EULAR2013 diagnostic criteria for systemic sclerosis
Intestinal lung disease confirmed by chest CT scan and lung function tests
Exclusion Criteria
Suffering from other autoimmune diseases
Uncontrolled high blood pressure, diabetes, and other endocrine disorders
Cardiovascular failure
Chronic renal failure
Hepatic impairment
Depression
Existence of life-threatening conflicts including severe platelet hemolysis below 40,000
Pregnancy and lactation
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rate of pulmonary involvement. Timepoint: Before and after the intervention (4-6 weeks later). Method of measurement: Using CT scan.
- Secondary Outcome Measures
Name Time Method