临床试验/DRKS00021597

DRKS00021597招募中未知

Orthostatic hypotension in patients with Parkinson’s disease and multiple system atrophy: the effect of lower limb compression stockings vs. abdominal binding therapy on physical activity – a single-blinded, randomized, controlled, cross-over study.

niversitätsklinikum Schleswig-Holstein Campus Kiel0 个研究点目标入组 17 人开始时间: 2020年5月6日最近更新: 2024年8月19日

适应症

试验速览

阶段: 未知
状态: 招募中
发起方
入组人数: 17

研究概览研究设计入排标准研究者记录与标识符相似试验

研究概览

简要总结

暂无简介。

研究设计

研究类型: Interventional
分配方式: Randomized controlled study
盲法: Blinded (masking used)

入排标准

年龄范围: 18 Years 至 100 Years（—）
性别: All

入选标准

•Patients will be included if they meet the following inclusion criteria: 1. Diagnosis of PD according to the UK Brain Bank Criteria or MSA, Parkinson type, 2. symptomatic OH (OHQ symptom assessment item 1 = 1), and 3. moderate OH (systolic/diastolic blood pressure drop of at least 20/10 mmHg within 3 min of standing or head-up tilt to at least 60° on a tilt table) or severe OH (BP drop = 30/15 mmHg).

排除标准

•Exclusion criteria comprise end stage PD (H & Y stage = 5), OH due to medication side effects (diuretics, alpha adrenergics for bladder disorder, sympatholytics, vasadilatators, antidepressants, antihypertensives), pharmacological treatment of OH (fludrocortisone, midodrine, droxidopa), other severe neurological, psychiatric or cardiac diseases, severe diabetes mellitus, severe peripheral neuropathy, pregnancy/breast feeding, and changes of the medical therapy in the 4 weeks prior to enrollment.

研究者

发起方

niversitätsklinikum Schleswig-Holstein Campus Kiel

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