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临床试验/NCT05510791
NCT05510791已完成不适用

Impact of Nuun SPORT on Subjective Exercise Performance in Male and Female Runners

University of Memphis2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2022年1月19日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
20
试验地点
2
主要终点
Heart rate

研究概览

简要总结

The study will examine the impact of the Nuun Sport tablets, as compared to water only, on heart rate, perceived exertion, and related outcomes in male and female runners, during and following the performance of a 60-minute treadmill run.

详细描述

As discussed in our prior applications (protocol FY2020-327 and FY2021-96), maintaining adequate hydration is essential to optimal health (Perrier, 2017), as well as athletic performance (Nuccio et al., 2017). When individuals exercise (in particular in a warm environment), they can lose excessive amounts of fluids through sweating, along with necessary electrolytes (e.g., sodium, potassium, chloride). With dehydration, individuals may feel sluggish and can experience impaired physical performance. (Kenefick, 2018)

Many attempts have been made to improve and measure the hydration status of active individuals (Love et al., 2018). This typically involves the ingestion of fluids leading up to activity (typically plain water), as well as the ingestion of fluids during the activity itself (water, along with a diluted carbohydrate/electrolyte beverage).

During aerobic exercise, the shift in fluid (intake versus losses) can affect electrolyte balance, with dehydration and potential adverse effects on performance and health (Perrier et al., 2021; Armstrong et al. 2021). A better understanding of rehydration methods and resultant efficacy would permit selection by an athlete of the optimal method for preventing dehydration to optimize physical performance and reduce potential deleterious effects.

It is well-accepted that electrolyte replenishment is of importance, both during and following exercise-to aid in rehydration for subsequent bouts. Electrolytes (sodium in particular) have been used for decades to aid athlete hydration and this has led to the development of various sport drinks-which also include small amounts of carbohydrate (e.g., Gatorade, Powerade).

The present study will examine the impact of the Nuun Sport tablets, as compared to water only, on heart rate, perceived exertion, and related outcomes: changes in body mass, changes in plasma volume, post-exercise urine volume, and changes in urine specific gravity in male and female runners, during and/or following the performance of a 60-minute treadmill run.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • body mass index (BMI) between 18-29.9 kg/m2 (not obese)
  • be able to fast overnight (>8 hrs)
  • consuming a minimum of two liters of water per day, on a regular basis
  • distance runners: run ≥ 15 miles/week, ≥ 3 runs/week, for at least the past 6 months
  • have completed a run of 60 minutes or more at least once per month for the past 6 months
  • normal resting blood pressure (systolic < 140 mmHg, diastolic < 90 mmHg) and heart rate (40-80bpm)
  • a negative verbal pre-study drug screen (alcohol abuse, amphetamines, benzodiazepines, cocaine, opioids, phencyclidine, barbiturates, cotinine) and no history of use of illicit drugs or other substances of abuse within 12 months of the screening visit

排除标准

  • tobacco user
  • if female, pregnant
  • history of known cardiovascular disease
  • more than 400mg caffeine intake per day
  • self-reported active infection or illness of any kind
  • consumption of alcohol-containing beverages within 48 hours of testing
  • consumption of caffeine-containing beverages within 48 hours of testing
  • strenuous exercise within 48 hours of testing

结局指标

主要结局

Heart rate

时间窗: 60 minutes into run

Heart rate will be measured before and every 10 minutes during the run using a chest strap

Specific gravity of urine

时间窗: 15 minutes after run

Specific gravity will be determined from a urine sample

Plasma Volume

时间窗: 5 minutes after run

Plasma Volume will be determine via blood sampling and determination of hematocrit and hemoglobin

Perceived exertion

时间窗: 60 minutes into run

Subjects will self-report perceived exertion using a scale from 0 (no exertion) to 10 (the most exertion)

Urine output (volume)

时间窗: 15 minutes post-run

Urine volume will be determine following collection

Body Mass

时间窗: 15 minutes post-run after urine collection

Body Mass will be measured

Urine output (mass)

时间窗: 15 minutes post-run

Urine mass will be determine following collection

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Richard Bloomer

Dean of the College of Health Sciences

University of Memphis

研究点 (2)

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