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Clinical Trials/NCT03297372
NCT03297372
Completed
Not Applicable

Clinical Study to Investigate Visual Performance of Hydrophobic Monofocal IOL: MicroPure 1.2.3.

Beaver-Visitec International, Inc.2 sites in 1 country121 target enrollmentOctober 23, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cataract
Sponsor
Beaver-Visitec International, Inc.
Enrollment
121
Locations
2
Primary Endpoint
monocular Corrected Distance Visual Acuity (CDVA) under photopic conditions
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The clinical investigation is a post-market clinical follow up study whereby patients undergoing routine cataract surgery will have monolateral implantation of a commercially available, CE approved monofocal intraocular lens MicroPure 1.2.3. (PhysIOL, Liège, Belgium).

Detailed Description

The examinations consist of visual acuity data, contrast sensitivity exams, slitlamp examinations and posterior capsule opacification (PCO) grading. Follow up will be up to 24 months postoperative.

Registry
clinicaltrials.gov
Start Date
October 23, 2017
End Date
September 8, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Cataractous eyes with no comorbidity
  • Availability, willingness and sufficient cognitive awareness to comply with examination procedures
  • Signed informed consent

Exclusion Criteria

  • Irregular astigmatism
  • Age of patient \< 45 years
  • Regular corneal astigmatism \> 0.75 D on study eye as measured by an automatic keratometer (regularity determined by the topography of the keratometry)
  • Difficulty for cooperation (distance from their home, general health condition)
  • Acute or chronic disease or illness that would increase risk or confound study results (e.g. diabetes mellitus (with retinopathy), immunocompromised, glaucoma etc...)
  • Any ocular comorbidity
  • History of ocular trauma or prior ocular surgery including refractive procedures
  • Capsule or zonular abnormalities that may affect postoperative centration or tilt of the lens (e.g. pseudoexfoliation syndrome, chronic Uveitis, Marfan's syndrome)
  • Pupil abnormalities (non-reactive, tonic pupils, abnormally shaped pupils or pupils that do not dilate under mesopic/scotopic conditions)
  • Complicated surgery

Outcomes

Primary Outcomes

monocular Corrected Distance Visual Acuity (CDVA) under photopic conditions

Time Frame: 6 months postoperative

The primary study end point is to show statistically equal visual acuity outcomes on monocular Corrected Distance Visual Acuity (CDVA) under photopic conditions compared to literature data on a monofocal hydrophobic IOL (Alcon - Acrysof SN60AT).

Secondary Outcomes

  • Posterior capsule opacification (PCO) grading(2 years postoperative)
  • Contrast Sensitivity(6 months postoperative)
  • Glistening assessment(2 years postoperative)
  • Uncorrected Distance Visual acuity (UDVA)(6 months postoperative)

Study Sites (2)

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