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Clinical Trials/NCT03306342
NCT03306342
Completed
Not Applicable

Clinical Study to Investigate Visual Performance, Patient Satisfaction and PCO Rate After Implantation of a Trifocal Hydrophobic IOL

Beaver-Visitec International, Inc.1 site in 1 country25 target enrollmentFebruary 2, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cataract
Sponsor
Beaver-Visitec International, Inc.
Enrollment
25
Locations
1
Primary Endpoint
binocular Uncorrected Distance Visual Acuity (UDVA)
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Prospective, controlled, single-surgeon, single-center post-market clinical follow up study to investigate the clinical outcomes of a hydrophobic trifocal IOL (PhysIOL POD F GF)

Detailed Description

This clinical investigation is a prospective, controlled, single-surgeon, single-center post-market clinical follow up study whereby patients undergoing routine cataract surgery will have bilateral implantation of trifocal intraocular lenses FineVision POD F GF (PhysIOL, Liège, Belgium). The study purpose is to obtain clinical data on visual acuity, contrast sensitivity, questionnaire outcomes and PCO rate on patients implanted with FineVision POD F GF. The device under investigation (FineVision POD F GF) is a trifocal glistening-free hydrophobic acrylic intraocular lens (IOL) manufactured by the sponsor of this study PhysIOL sa/nv. The IOL will be implanted as part of the routine cataract surgery on patients suffering from cataract development. In total 25 patients will be recruited for this clinical study and receive a bilateral implantation of FineVision POD F GF intraocular lens. Subjects participating in the trial will attend a total of 8 study visits (1 preoperative, 2 operative and 5 postoperative) over a period of 24 months.

Registry
clinicaltrials.gov
Start Date
February 2, 2018
End Date
November 11, 2020
Last Updated
4 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Cataractous eyes with no comorbidity
  • Spontaneously emitting the desire for spectacle independence after surgery and with realistic expectation.
  • Availability, willingness and sufficient cognitive awareness to comply with examination procedures
  • Signed informed consent

Exclusion Criteria

  • Irregular astigmatism
  • Age of patient \< 45 years
  • Regular corneal astigmatism \>0.75 dioptres by an automatic keratometer or biometer or \>1.0 dioptres if the steep axis of cylinder is between 90° and 120° in one or both eyes
  • Difficulty for cooperation (distance from their home, general health condition)
  • Acute or chronic disease or illness that would increase risk or confound study results (e.g. diabetes mellitus (with retinopathy), immunocompromised, glaucoma etc...)
  • Any ocular comorbidity
  • History of ocular trauma or prior ocular surgery including refractive procedures
  • Capsule or zonular abnormalities that may affect postoperative centration or tilt of the lens (e.g. pseudoexfoliation syndrome, chronic Uveitis, Marfan's syndrome)
  • Pupil abnormalities (non-reactive, tonic pupils, abnormally shaped pupils or pupils that do not dilate under mesopic/scotopic conditions)
  • AMD suspicious eyes (determined by OCT)

Outcomes

Primary Outcomes

binocular Uncorrected Distance Visual Acuity (UDVA)

Time Frame: 3 months postoperative

Statistically significant equality between literature data and data obtained in this study on binocular UDVA. UDVA is measured with ETDRS charts placed in 4m distance according to ISO 11979-7:2014

Secondary Outcomes

  • Corrected Distance Visual Acuity (CDVA)(3 months postoperative)
  • Distance Corrected Intermediate Visual Acuity (DCIVA)(3 months postoperative)
  • Contrast Sensitivity(3 months postoperative)
  • Manifested refraction(3 months postoperative)
  • Uncorrected Distance Visual Acuity (UDVA)(3 months postoperative)
  • Uncorrected Intermediate Visual Acuity (UIVA)(3 months postoperative)
  • Distance Corrected Near Visual Acuity (DCNVA)(3 months postoperative)
  • Uncorrected Near Visual Acuity (UNVA)(3 months postoperative)
  • Aberrometry(3 months postoperative)
  • PCO rate(2 years postoperative)
  • questionnaire(3 months postoperative)

Study Sites (1)

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