Comparison of the Effect of Collagen and Corticosteroid Intra-articular Injection on Function and Pain in Patients with First Carpometacarpal Joint Osteoarthritis

Shahid Beheshti University of Medical Sciences0 个研究点目标入组 50 人开始时间: 待定最近更新: 2024年3月6日

适应症

试验速览

暂无简介。

•Patients with first carpometacarpal osteoarthritis based on radiographic criteria grade 2 and 3 and have moderate to severe pain (VAS>=5) in the first carpometacarpal joint for at least 3 months, which is resistant to drug treatment.

•The patient's willingness to withdraw from the study at any stage of the design
•The presence of any acute or chronic infection of the joint or around the joint
•Any intra-articular injection of the first carpometacarpal joint was performed during the last three months.
•History of oral and systemic corticosteroid use in the last two weeks
•Use of NSAIDs within 2 weeks prior to injection
•Existence of inflammatory joint diseases such as rheumatoid arthritis, spondyloarthropathies, connective tissue diseases, gout, Paget's, septic arthritis
•History of neurological syndromes caused by entrapment of the peripheral nerves of the hands, such as carpal tunnel syndrome
•History of surgery in the hand
•Recent history of severe trauma to the hand
•Having a severe underlying disease such as uncontrolled diabetes
•Autoimmune and platelet disorders, treatment with anticoagulant and antiplatelet drugs within 10 days before injection
•Daily use of opioid and non-opioid analgesics
•Taking topical painkillers
•Hemarthrosis
•Erythema or psoriatic lesions at the injection site

发起方