Comparison of Cisatracurium with Atracurium with regard to intubating conditions and haemodynamic parameters during laryngoscopy in patients undergoing surgical procedures under general anaesthesia in a Tertiary Care Hospital in Sikkim.

Dr Thumu Jaisheel Gabriel Joseph1 个研究点分布在 1 个国家目标入组 70 人开始时间: 2023年8月8日最近更新: 2023年7月31日

试验速览

阶段: 4 期
状态: 尚未招募
发起方
入组人数: 70
试验地点: 1
主要终点: 1. To compare the effect of Muscle Relaxation between Atracurium & Cis Atracurium by comparing the ease of intubation

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This study aims at the comparison of two routinely used muscle relaxants which are Cisatracurium and Atracurium in regards to Haemodynamic conditions using ASA approved cardiac monitors, intubating conditions using stardardized gradings and compiling these results to conclude the better among the two drugs involved

研究设计

研究类型: Interventional
分配方式: Computer generated randomization
盲法: Participant and Investigator Blinded

入排标准

年龄范围: 18.00 Year(s) 至 60.00 Year(s)（—）
性别: All

入选标准

•American society of Anaesthesiology score [ASA] I and 2
•Both Males and Females
•Age between 18 years and 60 years
•Patients requiring endotracheal intubation undergoing General anaesthesia
•Patients undergoing only Elective Procedures.

排除标准

•Any systemic co-morbidity including uncontrolled hypertension and diabetes, Heart block, renal impairment (serum creatinine greater than 2mg/dl, hepatic impairment (trans-aminases greater than double the normal values), psychiatric disorders like Schizophrenia and Mania
•Patient not giving consent
•ASA Grade 3 and Grade 4 patients
•Patients with history of Bronchial Asthma
•Patient on any addictive drug or allergic to any drugs used in the trial
•Pregnant patient and lactating mothers
•Anticipated Difficult Airway (Mallampati Class III and IV, thyromental height < 6 cm, inter-incisor distance <3cm and cervical instability.).

结局指标

主要结局

1. To compare the effect of Muscle Relaxation between Atracurium & Cis Atracurium by comparing the ease of intubation

时间窗: 10 minutes after induction

2. To compare the change in haemodynamic parameters while using either Atracurium or Cis Atracurium

时间窗: 10 minutes after induction

次要结局

1. To compare the Time interval for first maintenance dose between Atracurium & Cis atracurium(2. To compare cost effectiveness between Atracurium & Cis atracurium)

研究者

发起方

Dr Thumu Jaisheel Gabriel Joseph

申办方类型

Other [Principal Investigator]

研究点 (1)

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