Analgesic Effect of Intra-articular Dexamethasone and Dexamethasone Added to Bupivacaine in Interscalene Brachial Plexus

Phase 4

Completed

• Conditions: Postoperative Pain
• Interventions: Procedure: serum phsyologic; Procedure: intraarticular dexamethasone; Procedure: interscalene dexamethasone

• Registration Number: NCT02026050
• Lead Sponsor: TC Erciyes University

Brief Summary

the aim of this study was to investigate the analgesic efficacy of intra articular dexamethasone administration for arthroscopic shoulder surgery.

Detailed Description

shoulder surgery can be very painful and interscalene brachial plexus block is the gold standard in the management of acute pain after shoulder surgery. various local anaesthetic mixtures can be used to prolong local anaesthesia duration and epinephrine , opioids and dexamethasone are frequently used for this purpose. dexamethasone has also been found the prolong the duration of lidocaine axillary blocks and intravenous regional anaesthesia. intraarticular administration of medicines can be used for management of joint pain and opioids , local anaesthetics and dexamethasone are used for this purpose.In addition, there are no studies available to compare the different treatment methods used in clinical practice directly.

Study Timeline

• Study First Submitted: 2013-12-30
• Study First Submitted QC: 2013-12-30
• Study Start: 2014-01
• Study First Posted: 2014-01-01
• Primary Completion: 2015-01
• Study Completion: 2015-01
• Status Verified: 2015-03
• Last Update Submitted: 2015-03-03
• Last Update Posted: 2015-03-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

• between 18-65 years
• arthroscopic shoulder surgery
• no known allergies to drugs
• ASA 1-2 patients

Exclusion Criteria

• history of diabetes
• history of chronic pain treatment
• pregnancy
• severe bronchopulmonary disease
• systemic glucocorticoid use

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
serum phsyologic	serum phsyologic	interscalene brachial plexus block was preoperative performed 30 ml 0.5 % bupivacaine+ 2ml serum phsyologic and after surgery 10 ml serum phsyologic administration for intraarticular
intraarticular dexamethasone	intraarticular dexamethasone	interscalene brachial plexus block was preoperative performed 30 ml 0.5 % bupivacaine+ 2 ml serum phsyologic and after surgery 2 ml 8 mg dexamethasone+ 8 ml serum phsyologic administration for intraarticular
interscalene dexamethasone	interscalene dexamethasone	interscalene brachial plexus was preoperative performed 30 ml 0.5 % bupivacaine added 2 ml 8mg dexamethasone and after surgery 10 ml serum phsyologic administration for intraarticular

Primary Outcome Measures

Name	Time	Method
analgesic consumption	postoperative 1 day	morphine consumption (patient controlled analgesia procedure) was recorded

Secondary Outcome Measures

Name	Time	Method
visual analog scale	postoperative 1 day	Visual analog scale on rest and movement was recorded

Trial Locations

Locations (1)

Erciyes university hospital; 🇹🇷 Kayseri, Turkey